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Atherosclerosis [a] is a pattern of the disease arteriosclerosis, [8] characterized by development of abnormalities called lesions in walls of arteries. This is a chronic inflammatory disease involving many different cell types and is driven by elevated levels of cholesterol in the blood. [ 9 ]
Arteriosclerosis, literally meaning "hardening of the arteries", is an umbrella term for a vascular disorder characterized by abnormal thickening, hardening, and loss of elasticity [3] of the walls of arteries; [4] this process gradually restricts the blood flow to one's organs and tissues and can lead to severe health risks brought on by atherosclerosis, which is a specific form of ...
Atherosclerosis is characterized by the build-up of plaque inside your blood vessels. It can lead to stenosis, which is a narrowing of your artery walls. Plaque is a fatty substance made up of:
As previously mentioned, the most common etiology of peripheral artery disease, especially in patients over 40 years old, is atherosclerosis. [19] Atherosclerosis is a narrowing of the arteries caused by lipid or fat buildup and calcium deposition in the wall of the affected arteries.
Atherosclerosis. Narrowing of the arteries can be caused by a process known as atherosclerosis (most common), arteriosclerosis, or arteriolosclerosis. This occurs when plaques (made up of deposits of cholesterol and other substances) build up over time in the walls of the arteries.
Image depicting atherosclerosis. Coronary occlusion is caused by the buildup of fats, cholesterol and other substances in and on the walls of the hearts arteries. [6] As plaque builds up, the arteries narrow. [7] Plaque often starts building up during childhood and is heavily influence by genetics, but also lifestyle and high blood cholesterol. [7]
Arterial occlusion can be classified into three types based on etiology: embolism, thrombosis, and atherosclerosis. These three types of occlusion underlie various common conditions, including coronary artery disease , [ 4 ] peripheral artery disease , [ 5 ] and pulmonary embolism , [ 6 ] which may be prevented by lowering risk factors.
Dual anti-platelet therapy and full anticoagulation are currently under investigation. The primary etiology of coronary ectasia in adults is atherosclerosis, thus treatment with statin therapy should be considered. Statin therapy may also reduce inflammation and matrix metalloproteinase activation which may reduce the progression of vessel ectasia.
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