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From 1969 onwards Giles Brindley [1] developed the sacral anterior root stimulator, with successful human trials from the early 1980s onwards. Although both sphincter and detrusor muscles are stimulated at the same time, the slower contraction kinetics of the bladder wall (smooth muscle tissue) compared to the sphincter (striated muscle tissue) mean that voiding occurs between the stimulation ...
Many studies have been initiated using the sacral nerve stimulation (SNS) technique to treat patients that suffer with urinary problems. [citation needed] When applying this procedure, proper patient screening is essential, because some disorders that affect the urinary tract (like bladder calculus or carcinoma in-situ) have to be treated differently.
In men, prostate surgery (prostatectomy, TURP, etc) and radiation therapy can damage the sphincter and cause stress incontinence. [7] Neurogenic bladder dysfunction can involve a malfunctioning urethral sphincter. [8] Urge incontinence can happen when the urethra cannot hold the urine in as the bladder contracts uncontrollably. [9]
It is located at the junction of the urethra with the urinary bladder and is continuous with the detrusor muscle, [1] [2] but anatomically and functionally fully independent from it. [3] It is composed of smooth muscle, so it is under the control of the autonomic nervous system, specifically the sympathetic nervous system.
The pelvic splanchnic nerves are featured as a key plot point in "Parasites Lost", a 2001 episode of the American animated TV comedy Futurama; when protagonist Philip J. Fry is infected with parasitic worms, the rest of the crew use micro-droids to enter his body with the intention of tickling the pelvic splanchnic ganglion to trigger a convulsive bowel movement that they believe will expel ...
The bladder also contains β 3 adrenergic receptors, and pharmacological agonists of this receptor are used to treat overactive bladder. The mucosa of the urinary bladder may herniate through the detrusor muscle. [6] This is most often an acquired condition due to high pressure in the urinary bladder, damage, or existing connective tissue ...
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