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Sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) typically start working within 30 to 60 minutes, while avanafil (Stendra) works within 15 to 30 minutes. As with most prescription ...
This metabolite also has an affinity for the PDE receptors, about 40% of that of sildenafil. Thus, the metabolite is responsible for about 20% of sildenafil's action. Sildenafil is excreted as metabolites predominantly in the feces (about 80% of administered oral dose) and to a lesser extent in the urine (around 13% of the administered oral dose).
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
Viagra works best when it’s taken at least 30 to 60 minutes before intimacy (and no more than four hours before). Eating food that’s high in fat can slow absorption and make Viagra work ...
Over the last 25 years, (ED) medications like Viagra and Cialis have become common fixtures in bedrooms around the world. These little pills have helped hundreds of millions of men get hard and ...
The active ingredient in Viagra, sildenafil provides relief from ED for around four hours per dose. Tadalafil . The active ingredient in Cialis, tadalafil is a long-lasting medication that can ...
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