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Lithium – Lithium is the "classic" mood stabilizer, the first to be approved by the US FDA, and still popular in treatment. Therapeutic drug monitoring is required to ensure lithium levels remain in the therapeutic range: 0.6 to 0.8 or 0.8–1.2 mEq/L (or millimolar).
The required dosage is slightly less than the toxic level (representing a low therapeutic index), requiring close monitoring of blood levels of lithium carbonate during treatment. [24] Within the therapeutic range there is a dose-response relationship. [25]
Other examples of drugs with a narrow therapeutic range, which may require drug monitoring both to achieve therapeutic levels and to minimize toxicity, include dimercaprol, theophylline, warfarin and lithium carbonate.
This may also be called standard range. In contrast, optimal (health) range or therapeutic target is a reference range or limit that is based on concentrations or levels that are associated with optimal health or minimal risk of related complications and diseases. For most substances presented, the optimal levels are the ones normally found in ...
Therapeutic drug monitoring (TDM) is a branch of clinical chemistry and clinical pharmacology that specializes in the measurement of medication levels in blood. Its main focus is on drugs with a narrow therapeutic range , i.e. drugs that can easily be under- or overdosed. [ 1 ]
Lithium is the mainstay in the management of bipolar disorder but it has a narrow therapeutic range and typically requires monitoring [18] Anticonvulsants, such as valproate, [19] carbamazepine, or lamotrigine; Atypical antipsychotics, such as quetiapine, [20] [21] risperidone, olanzapine, or aripiprazole
What makes the Deviate Nitro 2 stand out is its high comfort level despite the carbon plate. Plus, in true Puma fashion, the athletic shoes are breathable, reflective, and grippy for ultimate ...
Lithium citrate (Li 3 C 6 H 5 O 7) is a lithium salt of citric acid that is used as a mood stabilizer in psychiatric treatment of manic states and bipolar disorder ...
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