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Oral tablets containing 12.5 mg doxylamine succinate as well as oral capsules containing 25 mg doxylamine succinate were also previously available but were discontinued. [22] The combination of doxylamine and pyridoxine is available in the form of extended-and delayed-release oral tablets containing 10 to 20 mg doxylamine succinate and 10 to 20 ...
The main route of metabolism for agomelatine is hepatic through the CYP1A2 (90%) and CYP2C9/19 (10%); co-administration of strong CYP1A2 inhibitors (e.g., fluvoxamine) is contraindicated. [46] Agomelatine is well- absorbed with oral administration (≥80%), but it has very low oral bioavailability (~1%) due to extensive first-pass metabolism ...
The price of generic tadalafil can vary based on the dosage, but most versions of generic tadalafil cost $10 to $13 per tablet. When used daily, generic tadalafil can be less than $3 per pill ($79 ...
Levosulpiride, sold under the brand names Dislep and Sulpepta among others, is a dopamine antagonist medication which is used in the treatment of psychotic disorders like schizophrenia, major depressive disorder, nausea and vomiting, and gastroparesis.
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]
Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine. [4]
Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant and eugeroic (wakefulness promoter) medication used primarily to treat narcolepsy, [3] [8] [15] a sleep disorder characterized by excessive daytime sleepiness and sudden sleep attacks. [16]
Because clonazepam is effective in low milligram doses (0.5 mg clonazepam = 10 mg diazepam), [118] [119] it is said to be among the class of "highly potent" benzodiazepines. [120] The anticonvulsant properties of benzodiazepines are due to the enhancement of synaptic GABA responses, and the inhibition of sustained, high-frequency repetitive firing.