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Varenicline is indicated for use as an aid to smoking cessation treatment [5] and for the treatment of the signs and symptoms of dry eye disease. [6] Varenicline is used to help people stop smoking tobacco (smoking cessation). A meta-analysis found that 20% of people treated with varenicline remain abstinent from smoking at one year. [15]
Nicotine replacement therapy is as effective as medications, such as bupropion, in helping people quit smoking for at least six months. [16] All forms of nicotine replacement therapy, including nicotine gum, patches, nasal spray, inhalers, and lozenges, have similar success rates in terms of helping people stop smoking.
It has been found effective in several randomized clinical trials, including in the United States and New Zealand, [1] and is being investigated in additional trials in the United States and a non-inferiority trial in Australia in which it is being compared head-to-head with the smoking cessation aid varenicline (sold in the United States as ...
Antidepressants: The antidepressant bupropion is considered a first-line medication for smoking cessation and has been shown in many studies to increase long-term success rates. Although bupropion increases the risk of getting adverse events, there is no clear evidence that the drug has more or less adverse effects when compared to a placebo.
[2] [3] Another way to reduce nicotine withdrawal symptoms is to provide the body with an alternative source of nicotine (nicotine replacement therapy) for a temporary period and then taper this new nicotine intake. Other medication used for quitting smoking include bupropion, varenicline, cytisine, nortriptyline, and clonidine and psychedelics ...
New strategies are required to solve this significant health issue in the midst of these obstacles in order to promote smoking cessation. Immunotherapy-based methods, such as the use of vaccines to treat addiction, have been documented in the literature since the 1960s and 1970s. [ 23 ]
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