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Hepatomegaly is enlargement of the liver. [4] It is a non-specific medical sign, having many causes, which can broadly be broken down into infection, hepatic tumours, and metabolic disorder. Often, hepatomegaly presents as an abdominal mass. Depending on the cause, it may sometimes present along with jaundice. [1]
Mansonella ozzardi can cause symptoms that include arthralgias, headaches, fever, pulmonary symptoms, adenopathy, hepatomegaly, and pruritus. [1] Eosinophilia is often prominent but do not occur in all cases of Mansonelliasis. M. perstans can also present with Calabar-like swellings, hives, and a condition known as Kampala, or Ugandan eye worm. [2]
Congenital hepatic fibrosis usually presents in adolescent or young adulthood, but onset of signs and symptoms can range from early childhood through mid-life. Clinical features may vary but commonly include cholangitis, hepatomegaly and signs of portal hypertension. [citation needed]
Hepatomegaly Medical imaging : Longitudinal axis > 15.5 cm at the hepatic midline, or > 16.0 cm at the midclavicular line [ 14 ] Autopsy : Weight over upper limit of standard reference range, of 1,860 g (4.10 lb) in men [ 12 ] and 1,770 g (3.90 lb) in women.
The treatment of chronic liver disease depends on the cause. Specific conditions may be treated with medications including corticosteroids, interferon, antivirals, bile acids or other drugs. Supportive therapy for complications of cirrhosis include diuretics, albumin, vitamin K, blood products, antibiotics and nutritional therapy.
Treatments for heart failure include medications, an intra-aortic balloon pump, a ventricular assist device, heart valve replacements, extracorporeal membrane oxygenation (if the heart failure worsens suddenly and especially if an infection was the cause), an artificial heart, or a heart transplant (from a deceased human donor, or from a pig ...
Liver hemangiomas do not usually cause symptoms. [2] [5] They are usually small, with sizes up to 10 centimeters. [5] Their size tends to remain stable overtime. [5] However, if the hemangioma is large it can cause abdominal pain, a sense of fullness in right upper abdominal area, heart problems, and coagulation dysfunction.
Treatment of opisthorchiasis is usually accomplished with praziquantel. A single dose of praziquantel of 40 mg/kg is effective against opisthorchiasis (and also against schistosomiasis). [8] Despite the efficacy of this compound, the lack of acquired immunity to infection predisposes humans to reinfection in endemic regions.