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Midazolam, sold under the brand name Versed among others, is a benzodiazepine medication used for anesthesia, premedication before surgical anesthesia, and procedural sedation, and to treat severe agitation. [12] It induces sleepiness, decreases anxiety, and causes anterograde amnesia. [12]
Methylergonovine is intravenously administered with onset and duration of action similar to that of ergometrine. Its most common side effect is hypertension. Methylergonovine is recommended as a second-line therapy in treating postpartum hemorrhaging due to uterine atony according to both the American College of Obstetricians and Gynecologists ...
Etomidate replaces midazolam as the sedative. Drug companies have made it harder to buy midazolam for executions. Drug companies have made it harder to buy midazolam for executions. The etomidate was followed by rocuronium bromide , a paralytic, and finally, potassium acetate in place of the commonly used potassium chloride injection to stop ...
Remimazolam was found to have both a more rapid onset and a shorter duration than midazolam, and human clinical trials showed a faster recovery time and predictable, consistent pharmacokinetics, suggesting some advantages over existing drugs for these applications.
The administration of hydroxyzine in large amounts by ingestion or intramuscular administration during the onset of pregnancy can cause fetal abnormalities. When administered to pregnant rats, mice, and rabbits, hydroxyzine caused abnormalities such as hypogonadism with doses significantly above that of the human therapeutic range.
The term injection encompasses intravenous (IV), intramuscular (IM), subcutaneous (SC) and intradermal (ID) administration. [35] Parenteral administration generally acts more rapidly than topical or enteral administration, with onset of action often occurring in 15–30 seconds for IV, 10–20 minutes for IM and 15–30 minutes for SC. [36]
“Mad” is how one Middle East source reacted to US President Donald Trump’s announcement of a “takeover” of Gaza. So why would someone well versed in Trumpian tactics and the nuance of ...
A few drugs such as alcohol are absorbed by the lining of the stomach, and therefore tend to take effect much more quickly than the vast majority of oral medications which are absorbed in the small intestine. Gastric emptying time can vary from 0 to 3 hours, [2] and therefore plays a major role in onset of action for orally administered drugs ...