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The AutoAnalyzer is an early example of an automated chemistry analyzer using a special flow technique named "continuous flow analysis (CFA)", invented in 1957 by Leonard Skeggs, PhD and first made by the Technicon Corporation. The first applications were for clinical (medical) analysis.
Continuous flow analysis (CFA) is a general term that encompasses both segmented flow analysis (SFA) and flow injection analysis (FIA). In segmented flow analysis, a continuous stream of material is divided by air bubbles into discrete segments in which chemical reactions occur.
[4] With respect to molecular diffusion, dispersion occurs as a result of an unequal concentration of the introduced material throughout the bulk medium. When the dispersed material is first introduced into the bulk medium, the region at which it is introduced then has a higher concentration of that material than any other point in the bulk.
Process analytical technology (PAT) has been defined by the United States Food and Drug Administration (FDA) as a mechanism to design, analyze, and control pharmaceutical manufacturing processes through the measurement of critical process parameters (CPP) which affect the critical quality attributes (CQA).
The date and time, or more often the number of the control run, is plotted on the x-axis. A mark is made indicating how far the actual result was from the mean, which is the expected value for the control. Lines run across the graph at the mean, as well as one, two and three standard deviations to either side of the mean.
Entry of test requests onto the LIS system involves typing (or scanning where barcodes are used) in the laboratory number, and entering the patient identification, as well as any tests requested. This allows laboratory analyzers, computers and staff to recognize what tests are pending, and also gives a location (such as a hospital department ...
It works on almost any kind of charged molecule—including small inorganic anions, [2] large proteins, [3] small nucleotides, [4] and amino acids. However, ion chromatography must be done in conditions that are one pH unit away from the isoelectric point of a protein. [5] The two types of ion chromatography are anion-exchange and cation-exchange.
Surface of water has an immensely smooth nature that could be extended as large as the size of its container. The root-mean-square (RMS) roughness of water is 3.2 Å, as measured by X-ray reflectivity. [22] This feature makes Langmuir troughs a suitable candidate for synthesis and characterization of covalent monolayer sheets and even 2D polymers.