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This principle of "independent assortment" of genes is fundamental to genetic inheritance. [28] However, the frequency of recombination is actually not the same for all gene combinations. This leads to the notion of " genetic distance ", which is a measure of recombination frequency averaged over a (suitably large) sample of pedigrees.
Independent assortment occurs in eukaryotic organisms during meiotic metaphase I, and produces a gamete with a mixture of the organism's chromosomes. The physical basis of the independent assortment of chromosomes is the random orientation of each bivalent chromosome along the metaphase plate with respect to the other bivalent chromosomes.
Most recombination occurs naturally and can be classified into two types: (1) interchromosomal recombination, occurring through independent assortment of alleles whose loci are on different but homologous chromosomes (random orientation of pairs of homologous chromosomes in meiosis I); & (2) intrachromosomal recombination, occurring through ...
Meiosis generates gamete genetic diversity in two ways: (1) Law of Independent Assortment. The independent orientation of homologous chromosome pairs along the metaphase plate during metaphase I and orientation of sister chromatids in metaphase II, this is the subsequent separation of homologs and sister chromatids during anaphase I and II, it ...
Human fertilization is the union of an egg and sperm, occurring primarily in the ampulla of the fallopian tube. [1] The result of this union leads to the production of a fertilized egg called a zygote, initiating embryonic development. Scientists discovered the dynamics of human fertilization in the 19th century. [2]
[10] [11] In a random international sample of 11,548 men confirmed to be biological fathers by DNA paternity testing, the oldest father was found to be 66 years old at the birth of his child; the ratio of DNA-confirmed versus DNA-rejected paternity tests around that age is in agreement with the notion of general male infertility above age 65–66.
Many human genes, including one for a protein that controls cholesterol levels in the blood, show co-dominance too. People with the heterozygous form of this gene produce two different forms of the protein, each with a different effect on cholesterol levels.
This is an accepted version of this page This is the latest accepted revision, reviewed on 22 January 2025. Union of gametes of opposite sexes during the process of sexual reproduction to form a zygote This article is about fertilisation in animals and plants. For fertilisation in humans specifically, see Human fertilization. For soil improvement, see Fertilizer. "Conceive" redirects here. For ...