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Sumatriptan is effective for ending or relieving the intensity of migraine and cluster headaches. [9] It is most effective when taken early after the start of the pain. [9] Injected sumatriptan is more effective than other formulations. [10] Oral sumatriptan can be used also in the treatment of post-dural puncture headache. [11]
Triptans are a family of tryptamine-based drugs used as abortive medication in the treatment of migraines and cluster headaches. This drug class was first commercially introduced in the 1990s. While effective at treating individual headaches, they do not provide preventive treatment and are not considered a cure.
Cluster headaches may occasionally be referred to as "alarm clock headache" because of the regularity of their recurrence. Cluster headaches often awaken individuals from sleep. Both individual attacks and the cluster grouping can have a metronomic regularity; attacks typically strike at a precise time of day each morning or night.
Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) Short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA) Long-lasting autonomic symptoms with hemicrania (LASH) TACs can be differentiated by the length and frequency of recurrence of the headaches. [3]
Abortive therapy for cluster headaches includes subcutaneous sumatriptan (injected under the skin) and triptan nasal sprays. High flow oxygen therapy also helps with relief. [11] For people with extended periods of cluster headaches, preventive therapy can be necessary. Verapamil is recommended as first line treatment. Lithium can also be useful.
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
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Many people with chronic headaches fail to recognize foods or beverages as headache factors, because the consumption may not consistently cause headaches or the headaches may be delayed. [43] Many of the chemicals in certain foods can cause chronic headaches, including caffeine, nitrites, nitrates, tyramine, and alcohols. [ 44 ]
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