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Klippel–Trénaunay syndrome, formerly Klippel–Trénaunay–Weber syndrome [1] and sometimes angioosteohypertrophy syndrome and hemangiectatic hypertrophy, [2] is a rare congenital medical condition in which blood vessels and/or lymph vessels fail to form properly.
Maurice Klippel (30 May 1858 – 20 July 1942) was a French physician, for whom the conditions Klippel–Feil syndrome and Klippel–Trénaunay–Weber syndrome are named. He was born in Mulhouse , Haut-Rhin and studied medicine in Paris , earning his doctorate in 1889.
Weber's syndrome, also known as midbrain stroke syndrome or superior alternating hemiplegia, is a form of stroke that affects the medial portion of the midbrain. It involves oculomotor fascicles in the interpeduncular cisterns and cerebral peduncle so it characterizes the presence of an ipsilateral lower motor neuron type oculomotor nerve palsy and contralateral hemiparesis or hemiplegia.
Children with some overgrowth syndromes such as Klippel–Trénaunay syndrome can be readily detectable at birth. [3] In contrast, other overgrowth syndromes such as Proteus syndrome usually present in the postnatal period, characteristically between the second and third year of life. [ 2 ]
The medical community at times has used the terms Klippel-Trenaunay Syndrome and Klippel-Trenaunay-Weber Syndrome interchangeably. The consensus today is to distinguish K-T as hypertrophy and varicosity associated with port-wine staining; K-T-W ( more correctly called Parkes- Weber Syndrome) is similar but includes significant arteriovenous ...
Differences in leg length observed in DCMO can lead to problems with gait, joint pain and scoliosis. An orthopedic consultation should be made for patients with overgrowth involving bone. In Parkes-Weber syndrome, leg discrepancies > 2 cm require orthopedic evaluation. [9] Similar recommendations can be assumed for the limb overgrowth in DCMO.
Klippel–Trénaunay syndrome; Sturge–Weber syndrome; Histology. It is a vascular malformation wherein blood vessels proliferate along with accompanying mature fat ...
Syndromes associated with capillary malformations are: Sturge–Weber syndrome and Klippel–Trénaunay syndrome. [14] Capillary malformations can be treated with IPL-(Intensed-pulsed-light)-therapy or surgical resection. [3]
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