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The cuneate and gracile nuclei reside at the closed (lower) medulla, so the medial lemniscus is not formed at this level. Fibres from these nuclei will pass to the contralateral side of the brainstem, as the internal arcuate fibres. In the midbrain, it is situated dorsal to the substantia nigra, and medial to either red nucleus. [4]
Brain anatomy – forebrain, midbrain, hindbrain. The cerebral peduncles each form a lobe ventrally of the tegmentum, on either side of the midline. Beyond the midbrain, between the lobes, is the interpeduncular fossa, which is a cistern filled with cerebrospinal fluid [citation needed]. The majority of each lobe constitutes the cerebral crus.
The inferior colliculus is the principal midbrain nucleus of the auditory pathway and receives input from several peripheral brainstem nuclei, as well as inputs from the auditory cortex. Its inferior brachium (arm-like process) reaches to the medial geniculate nucleus of the diencephalon .
Fornix and septal nuclei; Subcortical areas: Septal nuclei; Amygdala; Nucleus accumbens; Diencephalic structures: Hypothalamus; Mammillary bodies; Anterior nuclei of thalamus; Other areas that have been included in the limbic system include the: Stria medullaris; Central gray and dorsal and ventral nuclei of Gudden
The paramedian pontine reticular formation (PMPRF) is involved in coordinating horizontal conjugate eye movements and saccades. To do so, besides projecting to the ibsilateral abducens nucleus, the PMPRF projects fibers through the MLF to the contralateral oculomotor nucleus (specifically, those of its motor neurons that innervate the medial rectus muscle).
The trochlear nucleus is located in the midbrain, at an intercollicular level between the superior colliculus and inferior colliculus. [3] As with all motor nuclei of cranial nerves, it is located near the midline (i.e. in the medial midbrain). [2] It is embedded within the medial longitudinal fasciculus.
The mesolimbic pathway transmits dopamine from the ventral tegmental area (VTA), which is located in the midbrain, to the ventral striatum, which includes both the nucleus accumbens and olfactory tubercle. [5] [6] The "meso" prefix in the word "mesolimbic" refers to the midbrain, or "middle brain", since "meso" means "middle" in Greek.
The brainstem, resembling a stalk, attaches to and leaves the cerebrum at the start of the midbrain area. The brainstem includes the midbrain, the pons, and the medulla oblongata. Behind the brainstem is the cerebellum (Latin: little brain). [7] The cerebrum, brainstem, cerebellum, and spinal cord are covered by three membranes called meninges.