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Drug-induced gingival enlargement (DIGE), also referred to as drug-induced gingival hyperplasia (DIGH) or drug-induced gingival overgrowth (DIGO), [1] is a side effect of many systemic medications for which the Gingervae are not the target receptor.
Lisinopril leaves the body completely unchanged in the urine. [1] [16] The half-life of lisinopril is 12 hours, and is increased in people with kidney problems. [1] [16] While the plasma half-life of lisinopril has been estimated between 12 and 13 hours, the elimination half-life is much longer, at around 30 hours. [18]
Gingival enlargement has a multitude of causes. The most common is chronic inflammatory gingival enlargement, when the gingivae are soft and discolored. This is caused by tissue edema and infective cellular infiltration caused by prolonged exposure to bacterial plaque, and is treated with conventional periodontal treatment, such as scaling and root planing.
Diabetes: "Gum disease and diabetes have a bidirectional relationship, meaning that gum disease can make it harder to control blood sugar levels, and uncontrolled diabetes can increase the risk of ...
Trauma, reactions to foreign bodies, or toxic reactions can also contribute to this non-plaque-induced gingivitis. Furthermore, genetics can play a significant role. Specifically, hereditary gingival fibromatosis is known to cause non-plaque-induced gingival lesions. However, sometimes, there is no specific cause for this form of gingival disease.
Gingivitis is a non-destructive disease that causes inflammation of the gums; [1] ulitis is an alternative term. [2] The most common form of gingivitis, and the most common form of periodontal disease overall, is in response to bacterial biofilms (also called plaque) that are attached to tooth surfaces, termed plaque-induced gingivitis.
The drugs that can cause hair loss include antihypertensive medications (such as ACE inhibitors or beta-blockers), cancer medications, statins, anticoagulants, antidepressants and medications that ...
If the gum recession is caused by gingivitis, the following symptoms may also be present: Puffy, red, or swollen (inflamed) gums; Gum bleeding while brushing or flossing; Bad breath ; In some cases, it is the treatment of gingivitis that reveals a gum recession problem, that was previously masked by the gums swelling.
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