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2. Type 3 innate lymphoid cells - Wikipedia

   en.wikipedia.org/wiki/Type_3_innate_lymphoid_cells

   This group of ILC produces IL-17 (especially IL-17A) [4] and IL-22. [5] Both cytokines can be produced by ILC 3 simultaneously or separately, provided that when IL-22 is produced alone it is a matter of NCR + ILC3. [5] ILC3 express IL-23R and the production of IL-17 and IL-22 is stimulated by IL-23 and IL-1β. [6]

3. Interleukin 3 - Wikipedia

   en.wikipedia.org/wiki/Interleukin_3

   Interleukin 3 is an interleukin, a type of biological signal that can improve the body's natural response to disease as part of the immune system. [10] In conjunction with other β common chain cytokines GM-CSF and IL-5, IL-3 works to regulate the inflammatory response in order to clear pathogens by changing the abundance of various cell populations via binding at the interleukin-3 receptor.

4. Innate lymphoid cell - Wikipedia

   en.wikipedia.org/wiki/Innate_lymphoid_cell

   These cytokines activate ILC2s, and therefore, an increased number of ILC2s, and type-2 cytokines (IL-4/5/13) are present in patients with allergic asthma. [3] They secrete IL-13, initiating allergic lung inflammation, and additionally promote Th2 differentiation, increasing the production of IL-13, and therefore amplifying the allergic ...

5. Blastic plasmacytoid dendritic cell neoplasm - Wikipedia

   en.wikipedia.org/wiki/Blastic_plasmacytoid...

   Tagraxofusp-erzs is a fusion protein consisting of interleukin 3 (i.e. IL-3) fused to diphtheria toxin. The fusion protein readily kills cultured pDC by binding to their IL-3 receptors to thereby gain entrance to the cells and then blocking these cells' protein synthesis (due to diphtheria toxin-mediated inhibition of eukaryotic elongation ...

6. U937 (cell line) - Wikipedia

   en.wikipedia.org/wiki/U937_(cell_line)

   U-937 cells mature and differentiate in response to a number of soluble stimuli, adopting the morphology and characteristics of monocytes, macrophages or dendritic cells. [3] U-937 cells are of myeloid lineage and thus secrete a large number of cytokines and chemokines either constitutively (e.g., IL-1 and GM-CSF) or in response to soluble stimuli.

7. Interleukin-3 receptor - Wikipedia

   en.wikipedia.org/wiki/Interleukin-3_receptor

   The interleukin-3 receptor is a molecule found on cells which helps transmit the signal of interleukin-3, a soluble cytokine important in the immune system. The gene coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes .

8. Natural killer cell - Wikipedia

   en.wikipedia.org/wiki/Natural_killer_cell

   Tumor cell detection results in activation of NK cells and consequent cytokine production and release. If tumor cells do not cause inflammation, they will also be regarded as self and will not induce a T cell response. A number of cytokines are produced by NKs, including tumor necrosis factor α , IFNγ, and interleukin . TNFα and IL-10 act as ...

9. Cytokine-induced killer cell - Wikipedia

   en.wikipedia.org/wiki/Cytokine-induced_killer_cell

   Cytokine-induced killer cells (CIK) cells are a group of immune effector cells featuring a mixed T- and natural killer (NK) cell-like phenotype.They are generated by ex vivo incubation of human peripheral blood mononuclear cells (PBMC) or cord blood mononuclear cells with interferon-gamma (), anti-CD3 antibody, recombinant human interleukin (IL)-1 and recombinant human interleukin (IL)-2.