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  2. Annuloaortic ectasia - Wikipedia

    en.wikipedia.org/wiki/Annuloaortic_ectasia

    For many years, the gold standard treatment for patients with aortic valve disease and aortic root aneurysms was to replace both the aortic valve and the ascending aorta with a composite graft. This also applies to patients with different levels of AI and annuloaortic ectasia, where the aortic valve may be largely preserved without any ...

  3. Aortic regurgitation - Wikipedia

    en.wikipedia.org/wiki/Aortic_regurgitation

    Aortic regurgitation (AR), also known as aortic insufficiency (AI), is the leaking of the aortic valve of the heart that causes blood to flow in the reverse direction during ventricular diastole, from the aorta into the left ventricle. As a consequence, the cardiac muscle is forced to work harder than normal.

  4. Valve-sparing aortic root replacement - Wikipedia

    en.wikipedia.org/wiki/Valve-sparing_aortic_root...

    Common features of both techniques of the replacement process are the clamping of the aorta and the use of a length of Dacron tube (also known as an "aortic graft"), typically 5 cm, to constrict the aortic root to the normal diameter, while the patient is cooled to 20°C and placed on life support. The procedure typically takes 4 to 6 hours in ...

  5. Aortic dissection - Wikipedia

    en.wikipedia.org/wiki/Aortic_dissection

    Aortic dissection explanation video. Aortic dissection (AD) occurs when an injury to the innermost layer of the aorta allows blood to flow between the layers of the aortic wall, forcing the layers apart. [3] In most cases, this is associated with a sudden onset of agonizing chest or back pain, often described as "tearing" in character.

  6. Ocrelizumab - Wikipedia

    en.wikipedia.org/wiki/Ocrelizumab

    Ocrelizumab, sold under the brand name Ocrevus, is a medication used for the treatment of multiple sclerosis.It is a humanized anti-CD20 monoclonal antibody. [8] It targets CD20 marker on B lymphocytes and is an immunosuppressive drug. [10]

  7. Valvular heart disease - Wikipedia

    en.wikipedia.org/wiki/Valvular_heart_disease

    In people with severe valvular disease, however, short-term risks of cardiovascular compromise after intramuscular injections may outweigh the benefits, and oral therapy may be considered instead of IM injections in this subset of patients. [28] Diseases of the aortic root can cause chronic aortic regurgitation.

  8. Aortic valve replacement - Wikipedia

    en.wikipedia.org/wiki/Aortic_valve_replacement

    [6] Aortic regurgitation, on the other hand, has many causes: degeneration of the cusps, endocarditis, bicuspid aortic valve, aortic root dilatation, trauma, connective tissue disorders such as Marfan syndrome or Ehlers-Danlos lead to imperfect closure of the valve during diastole, hence the blood is returning from the aorta towards the left ...

  9. Aortic aneurysm - Wikipedia

    en.wikipedia.org/wiki/Aortic_aneurysm

    A 6.5 cm AAA with a 3 cm lumen. An aortic aneurysm can occur as a result of trauma, infection, or, most commonly, from an intrinsic abnormality in the elastin and collagen components of the aortic wall. Aortic aneurysm development and progression have been directly associated with a deficiency of elastin as well as a loss of collagen type 1. [19]

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