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Kidney transplantation is a life-extending procedure. [87] The typical patient will live 10 to 15 years longer with a kidney transplant than if kept on dialysis. [88] The increase in longevity is greater for younger patients, but even 75-year-old recipients (the oldest group for which there is data) gain an average four more years of life.
It is classified as a medullary cystic kidney disease. The disorder is inherited in an autosomal recessive fashion and, although rare, is the most common genetic cause of childhood kidney failure. It is a form of ciliopathy. [4] Its incidence has been estimated to be 0.9 cases per million people in the United States, and 1 in 50,000 births in ...
In the context of chronic kidney disease, they are more accurately viewed as life-extending treatments, although if chronic kidney disease is managed well with dialysis and a compatible graft is found early and is successfully transplanted, the clinical course can be quite favorable, with life expectancy of many years.
The definitive treatment for hepatorenal syndrome is liver transplantation, and all other therapies can best be described as bridges to transplantation. [1] [23] While liver transplantation is by far the best available management option for HRS, the mortality of individuals with HRS has been shown to be as high as 25% within the first month ...
This issue is critical for young transplant recipients who have a life expectancy that is longer than the expected graft survival (i.e. how long a transplanted kidney lasts). Deceased donor kidneys typically last 5–15 years [42] and living donor kidneys typically last 10–30 years. [42]
Complications may also arise from enlarged/malformed kidneys, which may result in kidney failure and the child's going on dialysis or requiring a kidney transplant. Many individuals with prune belly syndrome have good physical and mental health, despite all the concerns. [8] With proper treatment, however, a longer, healthier life is possible.
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Cystic kidney disease refers to a wide range of hereditary, developmental, and acquired conditions [1] and with the inclusion of neoplasms with cystic changes, over 40 classifications and subtypes have been identified. Depending on the disease classification, the presentation may be at birth, or much later into adult life.