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Researchers have published conflicting reports concerning whether Blastocystis causes symptoms in humans, with one of the earliest reports in 1916. [2] The incidence of reports associated with symptoms began to increase in 1984, [3] with physicians from Saudi Arabia reporting symptoms in humans [4] and US physicians reporting symptoms in individuals with travel to less developed countries. [5]
In the early 2000s, Egyptian physicians identified 84 patients with diarrhea and enteritis apparently caused by Blastocystis hominis. After three days of nitazoxanide treatment, symptoms cleared and no fecal organisms were detectable in 36 (86%) of 42 treated patients and in 16 (38%) of 42 people who received placebo (P < .0001).
Blastocystis hominis is a single-celled eukaryotic organism that inhabits the gastrointestinal tract of humans and various animals. [1] This stramenopile exhibits significant genetic diversity and has become an organism of increasing scientific interest due to its widespread distribution and controversial role in human health. [ 2 ]
Up to 80 percent of dogs infected will have symptoms, but the mortality rate is only 5 to 8 percent. [5] Infectious canine hepatitis is a sometimes fatal infectious disease of the liver. [6] Canine herpesvirus is an infectious disease that is a common cause of death in puppies less than three weeks old. [7]
Blastocystis is a single-celled protozoan which infects the large intestine. Physicians report that patients with infection show symptoms of abdominal pain, constipation, and diarrhea. [54] [55] [56] One study found that 43% of IBS patients were infected with Blastocystis versus 7% of controls. [49]
Melarsoprol (for treatment of sleeping sickness caused by Trypanosoma brucei) Eflornithine (for sleeping sickness) Metronidazole (for vaginitis caused by Trichomonas) Tinidazole (for intestinal infections caused by Giardia lamblia) Miltefosine (for the treatment of visceral and cutaneous leishmaniasis, currently undergoing investigation for ...
Neonates, especially if preterm, are susceptible to M. hominis infection. [10] Meningoencephalitis in neonates has been described and M. hominis may be a significant causative agent of neonatal sepsis or meningitis. [11] M. hominis has been associated with chorioamnionits. [12] M. hominis is associated with miscarriage. [13]
Diagnosis is made by recognizing the combination of symptoms and abnormal blood tests that occur in infectious canine hepatitis. A rising antibody titer to CAV-1 is also seen. The disease can be confused with canine parvovirus because both will cause a low white blood cell count and bloody diarrhea in young, unvaccinated dogs. Treatment is ...
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