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  2. List of SJS-inducing substances - Wikipedia

    en.wikipedia.org/wiki/List_of_SJS-inducing...

    Acetaminophen, Panadol, Tylenol Penicillins [5] Phenytoin [5] Rivoraxaban [17] Xarelto: Sitagliptin [citation needed] Sulfonamides [2] Tetracycline [2 This page was ...

  3. Here's how Tylenol holds up against other common pain relievers

    www.aol.com/heres-tylenol-holds-against-other...

    Tylenol can be used to treat a few different conditions, such as: mild to moderate pain, fever, headaches, muscle aches, toothaches, backaches, colds, and discomfort from a vaccine, says Walia.

  4. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban, sold under the brand name Eliquis, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation through directly inhibiting factor Xa.

  5. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due to its orientation, it is able to interact with Trp-215 of the S4 pocket. The carbonyl oxygen group of the lactam moiety interacts with a water molecule and does not seem to interact with any residues in the S4 pocket. [23]

  6. Tylenol (brand) - Wikipedia

    en.wikipedia.org/wiki/Tylenol_(brand)

    The Tylenol murderer was never found, (though later James Lewis was a prime suspect [10]) and a US$100,000 reward offered by Johnson & Johnson remained unclaimed as of 2023. [11] [12] [13] Before the poisonings, Tylenol brands held around 35% of the US market for acetaminophen and in the immediate aftermath, fell to 8%.

  7. List of benzodiazepines - Wikipedia

    en.wikipedia.org/wiki/List_of_benzodiazepines

    The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses.

  8. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...

  9. Codeine/paracetamol - Wikipedia

    en.wikipedia.org/wiki/Codeine/paracetamol

    Codeine/paracetamol, also called codeine/acetaminophen and co-codamol, is a compound analgesic, comprising codeine phosphate and paracetamol (acetaminophen). Codeine/paracetamol is used for the relief of mild to moderate pain when paracetamol or non-steroidal anti-inflammatory drugs (NSAIDs; such as ibuprofen, aspirin, and naproxen) alone do not sufficiently relieve symptoms.

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