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Myelinated axons only allow action potentials to occur at the unmyelinated nodes of Ranvier that occur between the myelinated internodes. It is by this restriction that saltatory conduction propagates an action potential along the axon of a neuron at rates significantly higher than would be possible in unmyelinated axons (150 m/s compared from 0.5 to 10 m/s). [1]
Saltatory conduction provides one advantage over conduction that occurs along an axon without myelin sheaths. This is that the increased speed afforded by this mode of conduction assures faster interaction between neurons. On the other hand, depending on the average firing rate of the neuron, calculations show that the energetic cost of ...
Thus, the safety factor of saltatory conduction is high, allowing transmission to bypass nodes in case of injury. However, action potentials may end prematurely in certain places where the safety factor is low, even in unmyelinated neurons; a common example is the branch point of an axon, where it divides into two axons.
Saltatory conduction, a process by which nerve impulses are transmitted along axons Topics referred to by the same term This disambiguation page lists articles associated with the title Saltation .
Basic ways that neurons can interact with each other when converting input to output. Summation, which includes both spatial summation and temporal summation, is the process that determines whether or not an action potential will be generated by the combined effects of excitatory and inhibitory signals, both from multiple simultaneous inputs (spatial summation), and from repeated inputs ...
Further mathematical theories of nerve fiber conduction based on cable theory were developed by Cole and Hodgkin (1920s–1930s), Offner et al. (1940), and Rushton (1951). Experimental evidence for the importance of cable theory in modelling the behavior of axons began surfacing in the 1930s from work done by Cole, Curtis, Hodgkin, Sir Bernard ...
In biology, saltation (from Latin saltus 'leap, jump') is a sudden and large mutational change from one generation to the next, potentially causing single-step speciation.
The neurotransmitter most often associated with EPSPs is the amino acid glutamate, and is the main excitatory neurotransmitter in the central nervous system of vertebrates. [2]