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Leech secretions contain several bioactive substances with anti-inflammatory, anticoagulant and antimicrobial effects. [70] One active component of leech saliva is a small protein, hirudin. [72] It is widely used as an anticoagulant drug to treat blood-clotting disorders, and manufactured by recombinant DNA technology. [73] [74]
The price of leeches varied between one penny and threepence halfpenny each. In 1832 leeches accounted for 4.4% of the total hospital expenditure. The hospital maintained an aquarium for leeches until the 1930s. [15] The use of leeches began to become less widespread towards the end of the 19th century. [5]
Potentiates CNS sedatives, [3] chronic use might cause a reversible dry skin condition. [18] Khat: qat Catha edulis: Chronic liver dysfunction [3] [19] Kratom: Mitragyna speciosa: Hepatotoxicity [20] [19] Liquorice root Glycyrrhiza glabra: Hypokalemia, hypertension, arrhythmias, edema [5] Lobelia: asthma weed, pukeweed, vomit wort Lobelia inflata
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Vomiting is dangerous if gastric content enters the respiratory tract. Under normal circumstances, the gag reflex and coughing prevent this from occurring; however, these protective reflexes are compromised in persons who are under the influence of certain substances (including alcohol ) or even mildly anesthetized .
Hirudo is a genus of leeches of the family Hirudinidae. It was described by Carl Linnaeus in his landmark 1758 10th edition of Systema Naturae. [2] The two well-accepted species within the genus are: [3] Hirudo medicinalis Linnaeus, 1758; Hirudo nipponia Whitman, 1886
Although blood-sucking leeches do little direct harm to their victims, some transmit flagellates that can be very dangerous to their hosts. Some small tube-dwelling oligochaetes transmit myxosporean parasites that cause whirling disease in fish.
Wheaton says the leeches were created two different ways: For long shots, they used skateboard grip tape, and for the closeups used a combination of latex, blood makeup and rubber cement.