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  2. Pomalidomide - Wikipedia

    en.wikipedia.org/wiki/Pomalidomide

    Pomalidomide, sold under the brand names Pomalyst and Imnovid, [7] [8] is an anti-cancer medication used for the treatment of multiple myeloma and AIDS-related Kaposi sarcoma. [ 7 ] Pomalidomide was approved for medical use in the United States in February 2013, [ 10 ] and in the European Union in August 2013. [ 8 ]

  3. Should I Take Supplements to Sleep? What Experts Think - AOL

    www.aol.com/supplements-sleep-experts-think...

    For instance, alcohol and sleep is a tricky combination: a glass or two of red wine can certainly make it easier to fall asleep, but Pavlova says “you end up paying for it the second half of the ...

  4. Cereblon E3 ligase modulator - Wikipedia

    en.wikipedia.org/wiki/Cereblon_E3_ligase_modulator

    It is worth noticing however that, when comparing lenalidomide and pomalidomide, clinical relevance of higher in vitro potency is unclear since maximum tolerated dose of pomalidomide is 2 mg daily compared to 25 mg for lenalidomide, leading to 10-100 times lower plasma drug concentration of pomalidomide.

  5. Excessive daytime sleepiness - Wikipedia

    en.wikipedia.org/wiki/Excessive_daytime_sleepiness

    EDS can be a symptom of a number of factors and disorders. Specialists in sleep medicine are trained to diagnose them. Some are: Insufficient quality or quantity of night time sleep [5] Obstructive sleep apnea [6] Misalignments of the body's circadian pacemaker with the environment (e.g., jet lag, shift work, or other circadian rhythm sleep ...

  6. Magnesium is going viral as a natural sleep aid. But is it safe?

    www.aol.com/news/magnesium-going-viral-natural...

    Yes, it is generally safe for most people to take magnesium supplements daily as long as you stay within the recommended daily intake and are doing so at the recommendation of a health care ...

  7. Why you should think twice before taking a daily multivitamin ...

    www.aol.com/news/why-think-twice-taking-daily...

    Taking a vitamin completely out of its context and ramping up the dosage to a formulation that nature never really saw is not necessarily a good idea,” he said. “Mortality is decreased by ...

  8. Middle-of-the-night insomnia - Wikipedia

    en.wikipedia.org/wiki/Middle-of-the-night_insomnia

    Middle-of-the-night insomnia, or "sleep maintenance insomnia", also called terminal insomnia in contrast with "initial insomnia", is characterized by having difficulty returning to sleep after waking up during the night or very early in the morning. Initial or "sleep-onset" insomnia consists of having difficulty falling asleep at the beginning ...

  9. Non-24-hour sleep–wake disorder - Wikipedia

    en.wikipedia.org/wiki/Non-24-hour_sleep–wake...

    The possible causes of non-24-hour sleep-wake disorder are 2-fold: (1), extrinsic: isolation from daily light cycles (such as working in an environment completely devoid of natural lighting); [citation needed] and (2), intrinsic: where some condition, such as blindness or malfunctioning biochemical response to light in the subject, prevent ...