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Pigment dispersion syndrome (PDS) is an eye disorder that can lead to a form of glaucoma known as pigmentary glaucoma. It takes place when pigment cells slough off from the back of the iris and float around in the aqueous humor. Over time, these pigment cells can accumulate in the anterior chamber in such a way that they begin to clog the ...
Overproduction of pigment by these cells can block the trabecular meshwork through which fluid drains from the eye. The increased fluid in the eye leads to increased pressure, which can lead to glaucoma. In humans, this is sometimes known as pigment dispersion syndrome. [2]
Heterochromia iridum. Heterochromia is a variation in coloration most often used to describe color differences of the iris, but can also be applied to color variation of hair [1] or skin. Heterochromia is determined by the production, delivery, and concentration of melanin (a pigment). It may be inherited, or caused by genetic mosaicism ...
Elevated intraocular pressure can be caused by pigment dispersion, uveitis, hyphema or direct blocking of aqueous humor drainage system. [3] UGH syndrome is most commonly caused by anterior chamber IOLs and sulcus IOLs, but it can be seen with any type of IOL, including posterior chamber lenses and cosmetic iris implants.
Krukenberg's spindle is the name given to the pattern formed on the inner surface of the cornea by pigmented iris cells that are shed during the mechanical rubbing of posterior pigment layer of the iris with the zonules that are deposited as a result of the currents of the aqueous humor. The sign was described in 1899 by Friedrich Ernst ...
During gonioscopy (where the structures of the eye's anterior segment are examined), if an abundance of brown pigment is seen at or anterior to Schwalbe's line, a Sampaolesi line is said to be present. [1] [2] [3] The presence of a Sampaolesi line can signify pigment dispersion syndrome or pseudoexfoliation syndrome. [4] [5]
Dermatology. Pigmentation disorders are disturbances of human skin color. [1] There may be a loss or reduction, which may be related to loss of melanocytes or the inability of melanocytes to produce melanin or transport melanosomes correctly. [1]
MeSH. D006068. [edit on Wikidata] In ophthalmology, gonioscopy is a routine procedure that measures the angle between the iris and the cornea (the iridocorneal angle), using a goniolens (also known as a gonioscope) together with a slit lamp or operating microscope. [1][2] Its use is important in diagnosing and monitoring various eye conditions ...