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Yohimbine (/ joʊˈhɪmbiːn /), [2] also known as quebrachine, is an indole alkaloid derived from the bark of the African tree Pausinystalia johimbe; also from the bark of the unrelated South American tree Aspidosperma quebracho-blanco. Yohimbine is an α 2 -adrenergic receptor antagonist, and has been used in a variety of research projects.
Yohimbe is one of a number of Corynanthe evergreen species growing in West and Central Africa in lowland forests. The tree grows about 30m tall, with a straight bole that is rarely larger than 50–60 cm in diameter. The bark is grey to reddish-brown, with longitudinal fissures, easy to peel and bitter-tasting. The inner bark is pinkish and ...
It is a stereoisomer of yohimbine. [1] Rauwolscine is a central nervous system stimulant, a local anesthetic and a vague aphrodisiac. [1] Rauwolscine acts predominantly as a α 2 -adrenergic receptor antagonist. [2][3] It has also been shown to function as a 5-HT 1A receptor partial agonist and 5-HT 2A and 5-HT 2B receptor antagonist. [4][5][6]
Corynanthine, also known as rauhimbine, is an alkaloid found in the Rauvolfia and Corynanthe (including Pausinystalia) genera of plants. [1][2] It is one of the two diastereoisomers of yohimbine, the other being rauwolscine. [3][4] It is also related to ajmalicine. Corynanthine acts as an α 1 -adrenergic and α 2 -adrenergic receptor ...
In humans, goose bumps occur everywhere on the body, including the legs, neck, and other areas of the skin that have hair. In some people, they even occur in the face or on the head. I humans, goose bumps tends to occur across the whole body, especially when elicited by thermal or emotional stimuli, and only locally when elicited via tactile ...
Ajmalicine, also known as δ-yohimbine or raubasine, is an antihypertensive drug used in the treatment of high blood pressure. [1] It has been marketed under numerous brand names including Card-Lamuran, Circolene, Cristanyl, Duxil, Duxor, Hydroxysarpon, Iskedyl, Isosarpan, Isquebral, Lamuran, Melanex, Raunatin, Saltucin Co, Salvalion, and Sarpan. [1]
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