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  2. Rasmussen syndrome - Wikipedia

    en.wikipedia.org/wiki/Rasmussen_syndrome

    Rasmussen syndrome or Rasmussen's encephalitis is a rare inflammatory neurological disease, characterized by frequent and severe seizures, loss of motor skills and speech, hemiparesis (weakness on one side of the body), encephalitis (inflammation of the brain), and dementia. The illness affects a single cerebral hemisphere and generally occurs ...

  3. CDKL5 deficiency disorder - Wikipedia

    en.wikipedia.org/wiki/CDKL5_deficiency_disorder

    Cause. CDD is caused by pathogenic variants in the gene CDKL5. This gene provides instructions for making a protein (cyclin-dependent kinase -like 5) that is essential for normal brain development and function. [4] The CDKL5 protein is widely expressed in the brain, predominantly in nerve cells (neurons), with roles in cell proliferation ...

  4. Status epilepticus - Wikipedia

    en.wikipedia.org/wiki/Status_epilepticus

    40 per 100,000 people per year [2] Status epilepticus (SE), or status seizure, is a medical condition consisting of a single seizure lasting more than 5 minutes, or 2 or more seizures within a 5-minute period without the person returning to normal between them. [3][1] Previous definitions used a 30-minute time limit. [2]

  5. Progressive myoclonus epilepsy - Wikipedia

    en.wikipedia.org/wiki/Progressive_myoclonus_epilepsy

    Symptoms often include action or stimuli induced myoclonus, seizures, neuropathy, cognitive decline, and spike and wave or no cerebral discharges. [4] The prognosis of those diagnosed with PME is poor. The person often becomes reliant on a wheelchair, enters a vegetative state due to myoclonus, and has a shortened life expectancy. [4] [3]

  6. Dravet syndrome - Wikipedia

    en.wikipedia.org/wiki/Dravet_syndrome

    Dravet syndrome (DS), previously known as severe myoclonic epilepsy of infancy (SMEI), is an autosomal dominant genetic disorder which causes a catastrophic form of epilepsy, with prolonged seizures that are often triggered by hot temperatures or fever. [ 1 ] It is very difficult to treat with anticonvulsant medications.

  7. Epileptic spasms - Wikipedia

    en.wikipedia.org/wiki/Epileptic_spasms

    Epileptic spasms is an uncommon-to-rare epileptic disorder in infants, children and adults. One of the other names of the disorder, West syndrome, is in memory of the English physician, William James West (1793–1848), who first described it in an article published in The Lancet in 1841. [2] The original case actually described his own son ...

  8. Northern epilepsy syndrome - Wikipedia

    en.wikipedia.org/wiki/Northern_epilepsy_syndrome

    Seizure frequency is reduced to four to six seizures per year. [3] By this time, they are mentally and physically incapable to live without assistance due to the total mental degradation. Life expectancy is at least 50 years of age, which is shorter than the average worldwide age of 70. [4]

  9. Post-traumatic epilepsy - Wikipedia

    en.wikipedia.org/wiki/Post-traumatic_epilepsy

    Post-traumatic epilepsy (PTE) is a form of acquired epilepsy that results from brain damage caused by physical trauma to the brain (traumatic brain injury, abbreviated TBI). [1] A person with PTE experiences repeated post-traumatic seizures (PTS, seizures that result from TBI) more than a week after the initial injury. [ 2 ]

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