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Calcitonin. Calcitonin is a 32 amino acid peptide hormone secreted by parafollicular cells (also known as C cells) of the thyroid (or endostyle) in humans and other chordates [5] in the ultimopharyngeal body. [6] It acts to reduce blood calcium (Ca 2+), opposing the effects of parathyroid hormone (PTH). [7]
[2] α-CGRP is a 37-amino acid neuropeptide and is formed by alternative splicing [3] of the calcitonin/CGRP gene located on chromosome 11. β-CGRP is less studied. In humans, β-CGRP differs from α-CGRP by three amino acids and is encoded in a separate, nearby gene. [4] The CGRP family includes calcitonin (CT), adrenomedullin (AM), and amylin ...
Calcitonin receptor. The calcitonin receptor (CT) is a G protein-coupled receptor that binds the peptide hormone calcitonin and is involved in maintenance of calcium homeostasis, [5] particularly with respect to bone formation and metabolism. [6][7][8]
increases both systolic and diastolic blood pressure, glycogenolysis, lipolysis increases metabolism, etc. 4. Triiodothyronine. T 3. Amino acid derivative. peripheral tissue of thyroid gland. Thyroid follicular cell / Tyrosine. thyroid hormone receptor. nearly every cell in the body.
Shown is an example of such a shield, as engraved on a coin dating from 431 to 424 BCE. The thyroid gland received its modern name in the 1600s, when the anatomist Thomas Wharton likened its shape to that of an Ancient Greek shield or thyos. However, the existence of the gland, and of the diseases associated with it, was known long before then.
Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, along with numerous other biological functions. [1][2] In humans, the most significant compounds within this group are vitamin D 3 (cholecalciferol) and vitamin D 2 (ergocalciferol). [2][3]
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Calcitonin is a hormone secreted by the thyroid in humans. Calcitonin decreases osteoclast activity, and decreases the formation of new osteoclasts, resulting in decreased resorption. [ 4 ] Calcitonin has a greater effect in young children than in adults, and plays a smaller role in bone remodeling than PTH.