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Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. [6] Often, no symptoms are noticed initially. [10] As it progresses, bone pain, anemia, renal insufficiency, and infections may occur. [10]
Monoclonal gammopathy, also known as paraproteinemia, is the presence of excessive amounts of myeloma protein or monoclonal gamma globulin in the blood. It is usually due to an underlying immunoproliferative disorder or hematologic neoplasms, especially multiple myeloma. It is sometimes considered equivalent to plasma cell dyscrasia.
Myeloproliferative neoplasms (MPNs) are a group of rare blood cancers in which excess red blood cells, white blood cells or platelets are produced in the bone marrow. Myelo refers to the bone marrow, proliferative describes the rapid growth of blood cells and neoplasm describes that growth as abnormal and uncontrolled.
Received Pronunciation has been the subject of many academic studies, [2] and is frequently used as a model for teaching English to foreign learners. [ 3 ] [ page needed ] The widely repeated claim that only about two percent of Britons speak RP [ 2 ] is no more than a rough estimate and has been questioned by several writers, most notably by ...
Differences in pronunciation between American English (AmE) and British English (BrE) can be divided into . differences in accent (i.e. phoneme inventory and realisation).See differences between General American and Received Pronunciation for the standard accents in the United States and Britain; for information about other accents see regional accents of English.
Also, even though Nevada is the only state where the standard British pronunciation is significantly different to the standard American one due to the contrast between these vowels, there are dated British pronunciations that can still be heard such as ‘LouisiAHna’, ‘AlabAHma’ and ‘IndiAHna’ and people who say ask as ‘AHsk’, so ...
The English Pronouncing Dictionary (EPD) was created by the British phonetician Daniel Jones and was first published in 1917. [1] It originally comprised over 50,000 headwords listed in their spelling form, each of which was given one or more pronunciations transcribed using a set of phonemic symbols based on a standard accent.