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  2. Discovery and development of gliflozins - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    C-glucosides that have heterocyclic ring at the distal ring or proximal ring are better when it comes to anti-diabetic effect and physicochemical features all together. [ 3 ] [ 20 ] C-glucoside bearing thiazole at the distal ring on canagliflozin has shown good physicochemical properties that can lead to a clinical development, but still has ...

  3. Empagliflozin/linagliptin/metformin - Wikipedia

    en.wikipedia.org/wiki/Empagliflozin/linagliptin/...

    To reduce the risk of developing ketoacidosis (a serious condition where the body produces high levels of blood acids called ketones) after surgery, the FDA has approved changes to the prescribing information for SGLT2 inhibitor diabetes medications, recommending they be temporarily stopped before scheduled surgery.

  4. Empagliflozin - Wikipedia

    en.wikipedia.org/wiki/Empagliflozin

    Empagliflozin is an inhibitor of the sodium glucose co-transporter-2 (SGLT-2), and works by increasing sugar loss in urine. [2] Empagliflozin was approved for medical use in the United States and in the European Union in 2014. [13] [23] [24] It is on the World Health Organization's List of Essential Medicines. [25]

  5. Semaglutide linked to lower cognitive decline risk and ...

    www.aol.com/semaglutide-linked-lower-cognitive...

    After comparing the semaglutide group to groups taking sitagliptin, empagliflozin, or glipizide, the researchers found that semaglutide was associated with a lower risk for most of the 22 outcomes ...

  6. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    A European Medicines Agency review concluded that there is a potential increased risk of lower limb amputation (mostly affecting the toes) in people taking canagliflozin, dapagliflozin and empagliflozin. [17] In August 2018, the FDA issued a warning of an increased risk of Fournier gangrene in patients using SGLT2 inhibitors. [18]

  7. Serious Ozempic Side Effects, Confirmed: Here’s What to Know

    www.aol.com/lifestyle/serious-ozempic-side...

    "Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." Most people know that GLP-1 receptor agonist medications like Ozempic and Wegovy can cause relatively ...

  8. Glipizide - Wikipedia

    en.wikipedia.org/wiki/Glipizide

    Glipizide, sold under the brand name Glucotrol among others, is an anti-diabetic medication of the sulfonylurea class used to treat type 2 diabetes. [1] [2] It is used together with a diabetic diet and exercise. [1] [2] It is not indicated for use by itself in type 1 diabetes. [1] [2] It is taken by mouth.

  9. GLP-1 Drugs Benefit Brain and Heart Health, but May Cause ...

    www.aol.com/glp-1-drugs-benefit-brain-092222783.html

    A large study published in Nature Medicine reviewed the effects of GLP-1 drugs like Ozempic and Mounjaro on 175 different health outcomes. The findings show benefits for brain and heart health ...