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Examples include lichen planus, lichen sclerosus and lichen nitidus. It can also be associated with abrasion or drug use. [2] It has been observed in conjunction with the use of proton pump inhibitors, and might be a sign and/or symptom of lupus such as subacute cutaneous lupus erythematous, according to the case reports and reviews. [3] [4] [5 ...
Lichen planus may be categorized as affecting mucosal or cutaneous surfaces.. Cutaneous forms are those affecting the skin, scalp, and nails. [10] [11] [12]Mucosal forms are those affecting the lining of the gastrointestinal tract (mouth, pharynx, esophagus, stomach, anus), larynx, and other mucosal surfaces including the genitals, peritoneum, ears, nose, bladder and conjunctiva of the eyes.
Erythroderma is generalized exfoliative dermatitis, which involves 90% or more of the patient's skin. [3] The most common cause of erythroderma is exacerbation of an underlying skin disease, such as Harlequin-type ichthyosis, psoriasis, contact dermatitis, seborrheic dermatitis, lichen planus, pityriasis rubra pilaris or a drug reaction, such as the use of topical steroids. [4]
Drug/Drug Group Clinical Features [1]; NSAIDs: Purple, red, yellow, slate, or blue-grey pigmented macules on the extremities and trunk – drug eruption: Antimalarials: Blue-ish pigmentation of lower extremities, but can also involve the entire nail bed, nose, cheeks, forehead, ears, and oral mucosa
Desquamative gingivitis is a descriptive clinical term, not a diagnosis. [1] Dermatologic conditions cause about 75% of cases of desquamative gingivitis, and over 95% of the dermatologic cases are accounted for by either oral lichen planus or cicatricial pemphigoid. [1]
Melanonychia is a black or brown pigmentation of a nail, and may be present as a normal finding on many digits in Afro-Caribbeans, as a result of trauma, systemic disease, or medications, or as a postinflammatory event from such localized events as lichen planus or fixed drug eruption. [1]: 790 [2]: 665
Topical and intralesional (injected into the affected areas) corticosteroid drugs may be used, such as fluocinonide, clobetasol propionate or triamcinolone acetonide. Oral candidiasis may develop with long term topical steroid use, and sometimes antimycotics such as miconazole gel or chlorhexidine mouthwash are used to prevent this.
There is no standard treatment for pityriasis lichenoides chronica. Treatments may include ultraviolet phototherapy, sun exposure, oral antibiotics, and corticosteroid creams and ointments to treat rash and itching. [3] [5] One study identified the enzyme bromelain as an effective therapeutic option for pityriasis lichenoides chronica. [6]
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