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The example above is an example alloparalogy. Symparalogs are paralogs that evolved from gene duplication of paralogous genes in subsequent speciation events. From the example above, if the descendant with genes A1 and B underwent another speciation event where gene A1 duplicated, the new species would have genes B, A1a, and A1b.
Examples include the legs of a centipede, the maxillary and labial palps of an insect, and the spinous processes of successive vertebrae in a vertebrate's backbone. Male and female reproductive organs are homologous if they develop from the same embryonic tissue, as do the ovaries and testicles of mammals , including humans .
English: Top: An ancestral gene duplicates to produce two paralogs (histone H1.1 and 1.2).A speciation event produces orthologs in the two daughter species (human and chimpanzee).
HLA class I histocompatibility antigen, alpha chain E (HLA-E) also known as MHC class I antigen E is a protein that in humans is encoded by the HLA-E gene. [5] The human HLA-E is a non-classical MHC class I molecule that is characterized by a limited polymorphism and a lower cell surface expression than its classical paralogues.
Sirtuin 1, also known as NAD-dependent deacetylase sirtuin-1, is a protein that in humans is encoded by the SIRT1 gene. [5] [6] [7]SIRT1 stands for sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), referring to the fact that its sirtuin homolog (biological equivalent across species) in yeast (Saccharomyces cerevisiae) is Sir2.
For example, for AFF1 (AF4/FMR2 family, member 1), previous symbols and names are MLLT2 ("myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 2") and PBM1 ("pre-B-cell monocytic leukemia partner 1"), and synonyms are AF-4 and AF4. Authors of journal articles often use the latest official symbol and name ...
The elements of H n (X) are called homology classes. Each homology class is an equivalence class over cycles and two cycles in the same homology class are said to be homologous. [6] A chain complex is said to be exact if the image of the (n+1)th map is always equal to the kernel of the nth map.
Protein A, B and C are isoforms encoded from the same gene through alternative splicing.. A protein isoform, or "protein variant", [1] is a member of a set of highly similar proteins that originate from a single gene and are the result of genetic differences. [2]