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Arsphenamine was originally called "606" because it was the sixth in the sixth group of compounds synthesized for testing; it was marketed by Hoechst AG under the trade name "Salvarsan" in 1910. [ 7 ] [ 8 ] Salvarsan was the first organic antisyphilitic, and a great improvement over the inorganic mercury compounds that had been used previously.
When Hata injected compound 606, arsphenamine, into rabbits infected with syphilis, he found it to be effective against syphilis in vivo. [2] [6] It was called compound 606 because it was the 606th compound that Ehrlich and Hata tested. Arsphenamine was first thought to be ineffective when it was tested by Ehrlich's former assistants, so their ...
The drug in the kit was made by a German manufacturer Farbwerke vorm Meister Lucius & Bruning AG and is stamped with the date “3 February 1912”. It was sold by a British chemist, W Martindale, who added all the equipment to prepare injections. maker (Salvarsan): Farbwerke vorm Meister Lucius und Brüning, supplier: W Martindale
The first effective treatment, Salvarsan, was developed in 1910 by Sahachiro Hata in the laboratory of Paul Ehrlich. It was followed by the introduction of penicillin in 1943. [2] Many well-known figures, including Scott Joplin, Franz Schubert, Friedrich Nietzsche, Al Capone, and Édouard Manet are believed to have contracted the disease. [2]
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After performing "Pink Pony Club" and taking home the gramophone for best new artist at this year's Grammys on Sunday, Feb. 2, the "Casual" performer used her acceptance speech to advocate for ...
In 1910, Ehrlich and Hata announced their discovery, which they called drug "606", at the Congress for Internal Medicine at Wiesbaden. [136] The Hoechst company began to market the compound toward the end of 1910 under the name Salvarsan, now known as arsphenamine. [136] The drug was used to treat syphilis in the first half of the 20th century.