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On hourly treatment with the eye drops for a week, blood serum concentrations peaked at 150 pg/ml on average, with many patients remaining below the detection threshold of 80 pg/ml. The elimination half-life from the circulation is estimated at one to two hours; the substance is mainly (over 80%) excreted via the faeces.
Tobramycin/dexamethasone, sold under the brand name Tobradex, is a fixed-dose combination medication in the form of eye drops and eye ointment, marketed by Alcon. [1] [2] [3] The active ingredients are tobramycin (an antibiotic) and dexamethasone (a corticosteroid). [2] It is prescribed for the treatment of pink eye in combination with ...
The eye drops come in 25-count packages. Alcon issued the recall after a consumer complained of a “foreign material” they found in a sealed vial of the eye drops. When the company investigated ...
Cataract surgery in small animals such as dogs and cats is a routine ophthalmic procedure with a success rate of around 90%, and is usually better for eyes with relatively recent cataract development. The presence of other ocular problems may reduce the success rate. Procedures are similar to those for humans.
Cataracts cause the lens of the eye to become cloudy over time, but if they are left untreated, they can lead to complete blindness. While cataracts are unable to spread from one eye to another ...
The most important factor that must be taken into account when designing any type of drug delivery device, and specifically ocular devices, is the release rate of a drug. As discussed previously, the deliver rate and kinetics associated with drugs to the eye can reach levels that are toxic to the eye or could even cause undesirable side effects.
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Alcon was a subsidiary of Novartis until April 2019, when it was spun out into a separate publicly traded company. [3] [4] Alcon itself has a number of subsidiaries, including Aerie Pharmaceuticals, focused on therapies for glaucoma and other diseases of the eye, and WaveLight, which develops and manufactures laser eye surgery technologies. [5]
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