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Zaleplon, sold under the brand name Sonata among others, is a sedative and hypnotic which is used to treat insomnia. It is a nonbenzodiazepine or Z-drug of the pyrazolopyrimidine class. [ 10 ] It was developed by King Pharmaceuticals and approved for medical use in the United States in 1999.
Ethchlorvynol is a member of the class of sedative-hypnotic carbinols, which includes methylparafynol and tert-amyl alcohol.It is not a benzodiazepine, carbamate, or barbituric acid derivative, and its molecular structure is considerably simpler.
Chemical structure of the prototypical Z-drug zolpidem. Nonbenzodiazepines (/ ˌ n ɒ n ˌ b ɛ n z oʊ d aɪ ˈ æ z ɪ p iː n,-ˈ eɪ-/ [1] [2]), sometimes referred to colloquially as Z-drugs (as many of their names begin with the letter "z"), are a class of psychoactive, depressant, sedative, hypnotic, anxiolytic drugs that are benzodiazepine-like in uses, such as for treating insomnia [3 ...
In 2015, the American Geriatrics Society reviewed the safety information about eszopiclone and similar drugs and concluded that the "nonbenzodiazepine, benzodiazepine receptor agonist hypnotics (eszopiclone, zaleplon, zolpidem) are to be avoided without consideration of duration of use because of their association with harms balanced with their ...
Zaleplon - hypnotic (trade name Sonata) Indiplon - hypnotic; Ocinaplon - anxiolytic; Lorediplon - hypnotic; As they are not chemically related to the benzodiazepines despite their similar effect, such drugs—as well as the imidazopyridines and cyclopyrrones—are sometimes grouped together and referred to as "nonbenzodiazepines". Zaleplon
[61] [62] A meta-analysis of randomised controlled clinical trials that compared benzodiazepines to zopiclone or other Z drugs such as zolpidem and zaleplon has found few clear and consistent differences between zopiclone and the benzodiazepines in sleep onset latency, total sleep duration, number of awakenings, quality of sleep, adverse events ...
This multi-page article lists pharmaceutical drugs alphabetically by name. Many drugs have more than one name and, therefore, the same drug may be listed more than once. ...
Its mechanism of action is very similar to zolpidem and zaleplon in its pharmacology and can successfully substitute for zolpidem and zaleplon in animal studies. [ 43 ] [ 44 ] [ 45 ] Quazepam is selective for type I benzodiazepine receptors containing the α 1 subunit, similar to other drugs such as zaleplon and zolpidem .
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