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Glycolysis is the metabolic pathway that converts glucose (C 6 H 12 O 6) into pyruvate and, in most organisms, occurs in the liquid part of cells (the cytosol). The free energy released in this process is used to form the high-energy molecules adenosine triphosphate (ATP) and reduced nicotinamide adenine dinucleotide (NADH). [ 1 ]
The standard free energy change of the reaction is -25.1 kJ/mol. [6] Ethanol fermentation Yeast and other anaerobic microorganisms convert glucose to ethanol and CO 2 rather than pyruvate. Pyruvate is first converted to acetaldehyde by enzyme pyruvate decarboxylase in the presence of Thiamine pyrophosphate and Mg++. Carbon-dioxide is released ...
An example of a coupled reaction is the phosphorylation of fructose-6-phosphate to form the intermediate fructose-1,6-bisphosphate by the enzyme phosphofructokinase accompanied by the hydrolysis of ATP in the pathway of glycolysis. The resulting chemical reaction within the metabolic pathway is highly thermodynamically favorable and, as a ...
This reaction converts glucose 6-phosphate to fructose 6-phosphate in preparation for phosphorylation to fructose 1,6-bisphosphate. [2] The addition of the second phosphoryl group to produce fructose 1,6-bisphosphate is an irreversible step, and so is used to irreversibly target the glucose 6-phosphate breakdown to provide energy for ATP ...
Cori cycle. The Cori cycle (also known as the lactic acid cycle), named after its discoverers, Carl Ferdinand Cori and Gerty Cori, [1] is a metabolic pathway in which lactate, produced by anaerobic glycolysis in muscles, is transported to the liver and converted to glucose, which then returns to the muscles and is cyclically metabolized back to lactate.
Fructolysis refers to the metabolism of fructose from dietary sources. Though the metabolism of glucose through glycolysis uses many of the same enzymes and intermediate structures as those in fructolysis, the two sugars have very different metabolic fates in human metabolism. Under one percent of ingested fructose is directly converted to ...
Bioenergetics is a field in biochemistry and cell biology that concerns energy flow through living systems. [1] This is an active area of biological research that includes the study of the transformation of energy in living organisms and the study of thousands of different cellular processes such as cellular respiration and the many other metabolic and enzymatic processes that lead to ...
The ribose-5-phosphate can be transported into the nucleic acid metabolism, producing the basis of DNA and RNA monomers, the nucleotides. In meristematic cells, large amounts of DNA must be produced during the S-phase of a short cell cycle; this pathway is an extremely important part of the metabolism of these cells.