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While cell autonomous sex identity emphasizes the intrinsic sex-specific properties of individual cells, the interplay between CASI and hormonal influences plays a critical role in shaping an organism's overall sexual phenotype. CASI and hormones are not mutually exclusive but instead represent complementary mechanisms of sexual differentiation.
The optimality hypothesis states too much variability in the MHC can result in a failure of T-cells to distinguish themselves non-selves, and thereby increase the risk of autoimmune disease. This would confer greater fitness to individuals without a large degree MHC diversity. [6] [13] Autoimmune diseases are associated with MHC loci. In humans ...
To release active hormones quickly into the circulation, hormone biosynthetic cells may produce and store biologically inactive hormones in the form of pre-or prohormones. These can then be quickly converted into their active hormone form in response to a particular stimulus. [34] Eicosanoids are considered to act as local hormones. They are ...
Organic molecules such as sugars, amino acids, certain hormones, and messenger RNAs are known to be transported in the phloem through the cells called sieve tube elements. According to the hypothesis, the high concentration of organic substances, particularly sugar, inside the phloem at a source such as a leaf creates a diffusion gradient ...
Autocrine signaling is a form of cell signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine receptors on that same cell, leading to changes in the cell. [1] This can be contrasted with paracrine signaling, intracrine signaling, or classical endocrine signaling.
All known living things are made up of one or more cells [13] All living cells arise from pre-existing cells by division. The cell is the fundamental unit of structure and function in all living organisms. [14] The activity of an organism depends on the total activity of independent cells. [15] Energy flow (metabolism and biochemistry) occurs ...
The Organizational-Activational Hypothesis states that steroid hormones permanently organize the nervous system during early development, which is reflected in adult male or female typical behaviors. [1] In adulthood, the same steroid hormones activate, modulate, and inhibit these behaviors. [2]
Pancreas contain nearly 1 to 2 million islets of Langerhans (a tissue which consists cells that secrete hormones) and acini. Acini secretes digestive enzymes. [9] Alpha cells. The alpha cells of the pancreas secrete hormones to maintain homeostatic blood sugar. Insulin is produced and excreted to lower blood sugar to normal levels.