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Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Doxylamine succinate is the active ingredient in many over-the-counter sleep aids branded under various names. Doxylamine succinate and pyridoxine (Vitamin B6) are the ingredients of Diclegis, approved by the FDA in April 2013 becoming the only drug approved for morning sickness [46] with a class A safety rating for pregnancy (no evidence of risk).
Taking prenatal vitamins before pregnancy may decrease the risk. [3] Specific treatment other than a bland diet may not be required for mild cases. [2] [6] [3] If treatment is used the combination of doxylamine and pyridoxine is recommended initially. [3] [4] There is limited evidence that ginger may be useful.
Doxylamine succinate (12.5 mg/30 mL) (antihistamine/hypnotic) Phenylephrine (10 mg/30 mL) (nasal decongestant) Alcohol (10% by volume) The LiquiCap capsule version has the following active ingredients per pill, half the recommended adult dose: Acetaminophen (325 mg/pill) (pain reliever/fever reducer) Dextromethorphan (15 mg/pill) (cough ...
The growing popularity of drugs like Ozempic, Mounjaro and Wegovy, designed to help people with Type 2 diabetes and obesity, has raised new questions about what those drugs could mean for ...
While pyridoxine/doxylamine, a combination of vitamin B 6 and doxylamine, is effective in nausea and vomiting of pregnancy, [48] some have questioned its effectiveness in HG. [ 49 ] Ondansetron may be beneficial, however, there are some concerns regarding an association with cleft palate, [ 50 ] and there is little high-quality data. [ 46 ]
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Seed oils — plant-based cooking oils often used in processed, packaged foods — have been linked to an increased risk of colon cancer, according to a new study published in the medical journal Gut.
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