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  2. Collagen loss - Wikipedia

    en.wikipedia.org/wiki/Collagen_loss

    It may also cause blood vessels to constrict and reduce blood flow. Due to this, perioral collagen (connective tissue around the mouth below the skin) may show signs of damage. When collagen is lost in large amounts, it may cause wrinkles to emerge. Tobacco use can also result in slow collagen healing. [12]

  3. BAZAAR's Guide to Getting Rid of Forehead Wrinkles - AOL

    www.aol.com/lifestyle/five-ways-rid-forehead...

    Here are 10 dermatologist-recommended ways to get rid of forehead wrinkles, including products, treatments, neurotoxin injectables, ... "perioral" lines near your mouth, and neck lines or creases ...

  4. How to Get Rid of Wrinkles (and What Really Causes Them) - AOL

    www.aol.com/rid-wrinkles-really-causes-them...

    Symptoms of Wrinkles. Wrinkles are a symptom of aging, but some early signs of wrinkles can include fine lines. Later, deep wrinkles may form, particularly around the mouth, nose, eyes, and forehead.

  5. Papillon–Lefèvre syndrome - Wikipedia

    en.wikipedia.org/wiki/Papillon–Lefèvre_syndrome

    Early diagnosis and treatment is important to allow for prompt treatment to prevent long-term consequences such as tooth loss. [8]A diagnosis can be made by a urine analysis for low/no activity of the enzyme cathepsin C. [8]

  6. Periorbital hyperpigmentation - Wikipedia

    en.wikipedia.org/wiki/Periorbital_hyperpigmentation

    Periorbital hyperpigmentation, also known as hereditary dark circles, is characterized by darker skin around the eyes caused by the presence of additional melanin.It is an extremely common hereditary human characteristic and is frequently found on individuals with dark skin.

  7. These Pictures Will Help You Identify the Most Common ... - AOL

    www.aol.com/pictures-help-identify-most-common...

    What it looks like: Like seborrheic dermatitis, perioral dermatitis causes red, inflamed skin and small pustules around the nose and mouth. Other symptoms to note : Flare-ups can be itchy and ...

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