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For acne, the dosage is higher: it’s often started at 50 mg and then titrated up to 100 mg, and in some cases, 200 mg. Those dosages haven’t been studied in large, long-term clinical trials.
[61] [62] In addition, other studies have found that 100 mg/day spironolactone is significantly or near-significantly inferior to 500 mg/day flutamide in improving symptoms of acne and hirsutism. [ 63 ] [ 64 ] [ 65 ] One study compared placebo and dosages of spironolactone of 50, 100, 150, and 200 mg/day in the treatment of acne in women and ...
4. See if a vitamin or supplement might help. If you're not comfortable trying a prescription medication, there are some vitamins and supplements that could potentially help treat hormonal acne ...
Spironolactone blocks your sensitive receptors from your androgens (aka the "male" sex hormones), which helps reduce oil and acne. It's a once-a-day treatment that's typically super effective ...
Side effects of spironolactone in clinical studies for acne in women Side effect RCTs Tooltip Randomized controlled trials (n (ITT Tooltip Intention-to-treat analysis) = 326) Case series (n (ITT Tooltip Intention-to-treat analysis) = 663) Number % Number % Menstrual irregularities: 38: 13.4 (of 283) 216: 33.4 (of 646) Breast tenderness: 8: 2.5: ...
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