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Ground-glass opacity (GGO) is a finding seen on chest x-ray (radiograph) or computed tomography (CT) imaging of the lungs. It is typically defined as an area of hazy opacification (x-ray) or increased attenuation (CT) due to air displacement by fluid, airway collapse, fibrosis, or a neoplastic process. [1]
Ground glass opacity: No routine follow-up: CT after 6–12 months to check if persistent, then after 2 years and then another 2 years Part solid No routine follow-up: CT after 6–12 months: If unchanged and solid component remains <6mm: Annual CT for 5 years. Solid component ≥6mm: highly suspicious; Multiple nodules CT after 3–6 months.
There may be superimposed CT features such as mild ground-glass opacity, reticular pattern and pulmonary ossification. Probable UIP pattern: [4] Predominantly subpleural and basal; Often heterogenous distribution; Reticular pattern with peripheral traction bronchiectasis or bronchiolectasis; There may be mild ground-glass opacity; Indeterminate ...
Sagittal reformat from a CT scan of the chest showing air crescent sign in a patient with invasive fungal infection. There is a rounded cavity in the apical right upper lobe, with a non-dependant soft-tissue nodule within it. Also there is some subtle ground-glass opacity surrounding the lesion.
It tends to arise in the distal bronchioles or alveoli and is defined by a non-invasive growth pattern. This small solitary tumor exhibits pure alveolar distribution (lepidic growth) and lacks any invasion of the surrounding normal lung. If completely removed by surgery, the prognosis is excellent with up to 100% 5-year survival.
Low-dose high-resolution (1.25 mm) chest CT. HRCT is performed using a conventional CT scanner. However, imaging parameters are chosen so as to maximize spatial resolution: [1] a narrow slice width is used (usually 1–2 mm), a high spatial resolution image reconstruction algorithm is used, field of view is minimized, so as to minimize the size of each pixel, and other scan factors (e.g. focal ...
Acute presentation may reveal poorly defined a micro-nodular interstitial pattern and ground-glass opacities in the lower and mid lung zones. In addition to this, subacute presentations may show reticular nodular opacities in mid-to-lower lung zones. [1] Chronic forms may show fibrotic changes and appear like Idiopathic pulmonary fibrosis. [3]
It has been proposed that certain computed tomography findings such as ground-glass opacities, air bronchogram, spiculated margins, vascular convergence, and pleural retraction can predict the presence of EGFR mutation in patients with non-small cell lung cancer. [47]