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Atelectasis is the partial collapse or closure of a lung resulting in reduced or absent gas exchange. It is usually unilateral, affecting part or all of one lung. [2] It is a condition where the alveoli are deflated down to little or no volume, as distinct from pulmonary consolidation, in which they are filled with liquid.
Overdistension of alveoli and cyclic atelectasis (atelectotrauma) are the primary causes for alveolar injury during positive pressure mechanical ventilation.Severe injury to alveoli causes swelling of the tissues (edema) in the lungs, bleeding of the alveoli, loss of surfactant (decrease in lung compliance) and complete alveoli collapse ().
Atelectasis occurs when distending pressure of the alveolus is overcome by surface tension of fluid within the alveolus. Repeated atelectasis and re-inflation leads to atelectotrauma . Atelectotrauma , atelectrauma , cyclic atelectasis or repeated alveolar collapse and expansion ( RACE ) are medical terms for the damage caused to the lung by ...
The alveolar septum that separates the alveoli in the alveolar sac contains some collagen fibers and ... Without pulmonary surfactant, atelectasis is a certainty. ...
Alveolar lung disease may be divided into acute or chronic. Causes of acute alveolar lung disease include pulmonary edema (cardiogenic or neurogenic), pneumonia (bacterial or viral), systemic lupus erythematosus, [2] bleeding in the lungs (e.g., Goodpasture syndrome), [3] idiopathic pulmonary hemosiderosis, [4] and granulomatosis with polyangiitis.
Respiratory failure is classified as either Type 1 or Type 2, based on whether there is a high carbon dioxide level, and can be acute or chronic. In clinical trials, the definition of respiratory failure usually includes increased respiratory rate, abnormal blood gases (hypoxemia, hypercapnia, or both), and evidence of increased work of breathing.
It is often called a "collapsed lung", although that term may also refer to atelectasis. [1] A primary spontaneous pneumothorax is one that occurs without an apparent cause and in the absence of significant lung disease. [3] A secondary spontaneous pneumothorax occurs in the presence of existing lung disease.
Any process that increases the CC by increasing the closing volume (CV) can increase an individual's risk of hypoxemia, as the small airways may collapse during exhalation, leading to air trapping and atelectasis. A mnemonic for factors increasing closing capacity is ACLS-S: Age, Chronic bronchitis, LV failure, Smoking, Surgery.
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