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Polymorphisms in BDNF, DRD4, DAO, and TPH1 have been frequently associated with bipolar disorder and were initially associated in a meta-analysis, but this association disappeared after correction for multiple testing. [59] On the other hand, two polymorphisms in TPH2 were identified as being associated with bipolar disorder. [60]
Bipolar disorder is associated with elevated basal and dexamethasone elicited cortisol and adrenocorticotropic hormone (ACTH). These abnormalities are particularly prominent in mania, and are inversely associated with antipsychotic use. [97] The incidence of psychiatric symptoms associated with corticosteroids is between 6% and 32%.
A more recent twin study identified specific genes associated with bipolar disorder. ... There may also be imbalances in mood-regulating neurotransmitters (brain chemicals) like dopamine and ...
Polymorphisms in BDNF, DRD4, DAO, and TPH1 have been frequently associated with bipolar disorder and were initially associated in a meta-analysis, but this association disappeared after correction for multiple testing. [60] On the other hand, two polymorphisms in TPH2 were identified as being associated with bipolar disorder. [61]
Bipolar Disorder and Major Depressive Disorder have been closely linked due to the similar depressive symptoms and similar monoaminergic systems that have been thought to underlie these conditions. Much of the research for bipolar disorder is done in conjunction with studies of other diseases, most commonly schizophrenia and major depressive ...
[10] [11] A 2010 study found that "excellent performance" at school at age 15–16 was associated in males with a higher rate of developing bipolar disorder, but so was the poorest performance. [12] A 2005 study of young adult males found that poor performance on visuospatial tasks was associated with a higher rate of developing bipolar ...
“The therapy works by stimulating the brain’s production of serotonin, a neurotransmitter associated with mood elevation, and by helping to reset the body’s internal clock, or circadian ...
Biological psychiatry or biopsychiatry is an approach to psychiatry that aims to understand mental disorder in terms of the biological function of the nervous system.It is interdisciplinary in its approach and draws on sciences such as neuroscience, psychopharmacology, biochemistry, genetics, epigenetics and physiology to investigate the biological bases of behavior and psychopathology.
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