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Doxycycline, doxycycline monohydrate and doxycycline hyclate are yellow, crystalline powders with a bitter taste. The latter smells faintly of ethanol , a 1% aqueous solution has a pH of 2–3, and the specific rotation is [ α ] D 25 {\displaystyle [\alpha ]_{D}^{25}} −110° cm 3 /dm·g in 0.01 N methanolic hydrochloric acid .
These abscesses are formed from a blockage in a periodontal pocket and have a vital pulp associated with the tooth. [5] Usually treatment involves the drainage and irrigation of the abscess with antiseptic mouthwash (0.2% Chlorhexidine) and antibiotic therapy is rarely required. [8]
Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.
Topical anesthetic agents are typically intraorally to control pain or irritation caused by toothache, teething, or sores in or around the mouth. Topical anesthetics are available by prescription or over-the-counter. They are available in sprays, dental paste, dental gels, lozenges, ointments and solutions.
Doxycycline. Doxycycline is a semi-synthetic tetracycline that has been studied for dental and medical applications. Its effects on diseases like periodontitis and cancer has been investigated. [2] Doxycycline is nearly completely absorbed with a bioavailability about 95% in average and a 20% reduction with co-administration of food.
Other side effects include poor tooth development if used by children less than eight years of age, kidney problems, and sunburning easily. [3] Use during pregnancy may harm the baby. [3] It works by inhibiting protein synthesis in bacteria. [3] Tetracycline was patented in 1953 [6] and was approved for prescription use in 1954.