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Melanin is the pigment that gives skin its color; it is produced by skin cells called melanocytes. Variations in genes that are part of the immune system or part of melanocytes have both been associated with vitiligo. [2] It is also thought to be caused by the immune system attacking and destroying the melanocytes of the skin. [18]
Genetics, sun exposure, and some drugs are the three main factors that contribute to skin pigmentation. [4] The most frequent cause of low melanin concentration (hypopigmentation) is prior skin trauma, which includes skin lesions including blisters, burns, infections, exposure to chemicals, and other wounds. The skin will appear paler than the ...
The pigment loss can be partial (injury to the skin) or complete (caused by vitiligo). It can be temporary (from tinea versicolor) or permanent (from albinism). [1] Most commonly, depigmentation of the skin is linked to people born with vitiligo, which produces differing areas of light and dark skin. Monobenzone also causes skin depigmentation.
Causes of white spots on nails. The presence of white spots on your nails can mean a number of things. Experts say the discoloration is most commonly due to injury and is usually not a major cause ...
In short, melasma is a chronic skin condition that appears as darkened areas on the face due to an overproduction of melanin, says Gina Charles, MO, a family physician specializing in skincare. It ...
Some common genetic causes include mutations in the tyrosinase gene or OCA2 gene. [3] [4] As melanin pigments tend to be in the skin, eye, and hair, these are the commonly affected areas in those with hypopigmentation. [2] Hypopigmentation is common and approximately one in twenty have at least one hypopigmented macule.
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Nevus depigmentosus is a loss of pigment in the skin which can be easily differentiated from vitiligo. Although age factor has not much involvement in the nevus depigmentosus but in about 19% of the cases these are noted at birth. Their size may however grow in proportion to growth of the body.