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Compared with other existing imaging technologies, laser speckle contrast imaging has several obvious advantages. It can uses simple and cost-effective instrument to return excellent spatial and temporal resolution imaging. And due to these strengths, laser speckle contrast imaging has been involved in mapping blood flow for decades.
Laser Doppler imaging (LDI) is an imaging method that uses a laser beam to image live tissue. When the laser light reaches the tissue, the moving blood cells generate Doppler components in the reflected (backscattered) light. The light that comes back is detected using a photodiode that converts it into an electrical signal.
Therefore, there is an urgent need for a way to measure blood flow. However, blood flow is difficult to measure because of sensitivity and stability of the measurement as it depends on magnitude of flow, location, and the diameter of individual vessels. [2] Current imaging modalities used to measure blood flow include Doppler ultrasound, PET ...
Velocity measurements of blood flow are also used in other fields of medical ultrasonography, such as obstetric ultrasonography and neurology. Velocity measurement of blood flow in arteries and veins based on Doppler effect is an effective tool for diagnosis of vascular problems like stenosis. [18]
The photoacoustic Doppler effect is a type of Doppler effect that occurs when an intensity modulated light wave induces a photoacoustic wave on moving particles with a specific frequency. The observed frequency shift is a good indicator of the velocity of the illuminated moving particles. A potential biomedical application is measuring blood flow.
Doppler ultrasonography is medical ultrasonography that employs the Doppler effect to perform imaging of the movement of tissues and body fluids (usually blood), [1] [2] and their relative velocity to the probe. By calculating the frequency shift of a particular sample volume, for example, flow in an artery or a jet of blood flow over a heart ...
Doppler measurements using Doppler effect can show the direction of the blood flow and its relative velocity and color Doppler is the provision of color to help interpret the image, showing for example, the blood flow towards the probe in one color and that flowing away another. Whilst the equipment itself is costly, the procedure is not.
SV-OCT uses the inter-frame variance of image intensities to compute blood flow. Areas that have high flow will have higher motion of scattering particles and this information is encoded in the speckle pattern. [citation needed] SV-OCT has advantages for microvasculature imaging due to its high sensitivity and independence to the Doppler angle.
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