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During pregnancy, there are two main kinds of antidepressants used during pregnancy; tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs). Once prescribed, anti-depressant medication has been found to be extremely effective in treating antenatal depression.
Breastfeeding is associated with improved social and emotional health and development of the child. [1] The breastfeeding activity induces calming and analgesic effects in the infant. During this activity, their heart and metabolic rates decrease and their sensitivity to pain is reduced. [15]
For many antidepressants, this risk is highest during the first few weeks and months of treatment. ... or are breastfeeding. Once prescribed, escitalopram may take some time to start working. Don ...
Sertraline has a low level of exposure of an infant through the breast milk and is recommended as the preferred option for the antidepressant therapy of breast-feeding mothers. [ 84 ] [ 85 ] There is 29–42% increase in congenital heart defects among children whose mothers were prescribed sertraline during pregnancy, [ 14 ] [ 15 ] with ...
(Zuranolone can be taken alongside widely used antidepressants). The FDA fast-tracked zuranolone in 2017 — a step taken for drugs that could treat serious conditions and fill an unmet medical need.
Fluoxetine taken during pregnancy is associated with a significant increase in congenital heart defects in newborns. [12] [13] It has been suggested that fluoxetine therapy may be continued during breastfeeding if it was used during pregnancy or if other antidepressants were ineffective. [14]
A new Canadian study suggests that women who take antidepressants during pregnancy may be more likely to give birth to children with autism.
The use of SSRIs for the treatment of PPD is not a contraindication for breastfeeding. While antidepressants are excreted in breastmilk, the concentrations recorded in breastmilk are very low. [131] [132] Extensive research has shown that the use of SSRI's by women who are lactating is safe for the breastfeeding infant/child.
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