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A lysosome (/ ˈ l aɪ s ə ˌ s oʊ m /) is a single membrane-bound organelle found in many animal cells. [1] [2] They are spherical vesicles that contain hydrolytic enzymes that digest many kinds of biomolecules. A lysosome has a specific composition, of both its membrane proteins and its lumenal proteins.
Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins. The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the ...
CD68 (also called gp110 or macrosialin) [5] is a heavily glycosylated integral membrane protein whose structure consists of a mucin-like domain followed by a proline-rich hinge; a single LAMP-like domain; a transmembrane region and a short cytoplasmic tail. CD molecules are leucocyte antigens on cell surfaces.
Another example is the complex "pepin" system of Thiomargarita species, especially T. magnifica. [11] The organelles of the endomembrane system are related through direct contact or by the transfer of membrane segments as vesicles. Despite these relationships, the various membranes are not identical in structure and function.
Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, band 4 (13q34).
For example the 'phospholipid bilayer' could refer to the height or depth dimension (corner to corner is the only dimension that fits visually). The dimension line should not be at an angle. It may be better to stick to Transport, Integral, Globular, Peripheral and Surface proteins (or similar classification) in the image and make finer ...
Every year in the early winter, a swarm of dri-fit quarter-zips descends upon some mammoth, labyrinthian hotel to whisper, whine, schmooze and booze. These are MLB’s winter meetings, an annual ...
For example, in epithelial cells, a special process called transcytosis allows some materials to enter one side of a cell and exit from the opposite side. Also, in some circumstances, late endosomes/MVBs fuse with the plasma membrane instead of with lysosomes, releasing the lumenal vesicles, now called exosomes, into the extracellular medium.