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Dermatopolymyositis is a family of myositis disorders that includes polymyositis and dermatomyositis. As such, it includes both a distinctive skin rash and ...
Dermatomyositis is considered a type of inflammatory myopathy. [1] Diagnosis is typically based on some combination of symptoms, blood tests, electromyography, and muscle biopsies. [2] Eighty percent of adults [5] and sixty percent of children with juvenile dermatomyositis have a myositis-specific antibody (MSA). [6]
Juvenile dermatomyositis (JDM) is an idiopathic inflammatory myopathy (IMM) of presumed autoimmune dysfunction resulting in muscle weakness among other complications. It manifests itself in children; it is the pediatric counterpart of dermatomyositis.
Polymyositis and the associated inflammatory myopathies have an associated increased risk of cancer. [3] The features they found associated with an increased risk of cancer were older age, age greater than 45, male sex, difficulty swallowing, death of skin cells, cutaneous vasculitis, rapid onset of myositis (<4 weeks), elevated creatine kinase, higher erythrocyte sedimentation rate and higher ...
Although they vary in particulars, polymyositis, dermatomyositis and inclusion body myositis are idiopathic inflammatory myopathies (IIM) [1] primarily characterized by chronic inflammation of human skeletal muscle tissue [2] that ultimately causes the necrosis of muscle cells.
IBM stands for "inclusion body myositis: not "inclusion body myopathy." [6] The 'inclusion body' refers to a histological finding of rimmed vacuoles in muscle tissue. [6] However, IBM does not refer to the collection of diseases that feature these inclusion bodies. It refers to a specific disease entity. [6]
Diagnosing MCTD involves identification of inflammatory myopathy that is histologically and clinically identical to polymyositis (PM). [30] [31] [32] The majority of persons with MCTD do not experience clinical weakness. People with MCTD typically have mild myositis, with normal muscle enzymes and electromyographic results. In fact, some people ...
In medicine, myopathy is a disease of the muscle [1] in which the muscle fibers do not function properly. Myopathy means muscle disease ( Greek : myo- muscle + patheia -pathy : suffering ). This meaning implies that the primary defect is within the muscle, as opposed to the nerves (" neuropathies " or " neurogenic " disorders) or elsewhere (e.g ...