Search results
Results from the WOW.Com Content Network
When a non-competitive inhibitor is added the Vmax is changed, while the Km remains unchanged. According to the Lineweaver-Burk plot the Vmax is reduced during the addition of a non-competitive inhibitor, which is shown in the plot by a change in both the slope and y-intercept when a non-competitive inhibitor is added. [8]
On the other hand, the V max will decrease relative to an uninhibited enzyme. On a Lineweaver-Burk plot, the presence of a noncompetitive inhibitor is illustrated by a change in the y-intercept, defined as 1/V max. The x-intercept, defined as −1/K M, will remain the same. In competitive inhibition, the inhibitor will bind to an enzyme at the ...
For example, an inhibitor might compete with substrate A for the first binding site, but be a non-competitive inhibitor with respect to substrate B in the second binding site. [26] Traditionally reversible enzyme inhibitors have been classified as competitive, uncompetitive, or non-competitive, according to their effects on K m and V max. [14]
If the inhibitor is different from the substrate, then competitive inhibition will increase Km while Vmax remains the same, and non-competitive will decrease Vmax while Km remains the same. However, under substrate inhibiting effects where two of the same substrate molecules bind to the active sites and inhibitory sites, the reaction rate will ...
Compressor characteristic is a mathematical curve that shows the behaviour of a fluid going through a dynamic compressor.It shows changes in fluid pressure, temperature, entropy, flow rate etc.) with the compressor operating at different speeds.
The limiting case of the Venturi effect is when a fluid reaches the state of choked flow, where the fluid velocity approaches the local speed of sound. When a fluid system is in a state of choked flow, a further decrease in the downstream pressure environment will not lead to an increase in velocity, unless the fluid is compressed.
Uncompetitive inhibition (which Laidler and Bunting preferred to call anti-competitive inhibition, [1] but this term has not been widely adopted) is a type of inhibition in which the apparent values of the Michaelis–Menten parameters and are decreased in the same proportion.
The breech and the barrel must resist the high-pressure gases without damage. Although the pressure initially rises to a high value, the pressure starts dropping when the projectile has traveled some distance down the barrel. Consequently, the muzzle end of the barrel does not need to be as strong as the chamber end. [5]