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2. Losartan - Wikipedia

   en.wikipedia.org/wiki/Losartan

   Losartan is excreted in the urine, and in the feces via bile, as unchanged drug and metabolites. [44] About 4% of an oral dose is excreted unchanged in urine, and about 6% is excreted in urine as the active metabolite. [44] The terminal elimination half-lives of losartan and EXP3174 are about 1.5 to 2.5 hours and 3 to 9 hours, respectively. [44]

3. Losartan/hydrochlorothiazide - Wikipedia

   en.wikipedia.org/wiki/Losartan/hydrochlorothiazide

   Losartan/hydrochlorothiazide, sold under the brand name Hyzaar among others, is a fixed-dose combination medication used to treat high blood pressure when losartan is not sufficient. [1] [2] It consists of losartan, an angiotensin II receptor blocker; and hydrochlorothiazide, a thiazide diuretic. [1] [2] It is taken by mouth. [1] [2]

4. Angiotensin II receptor blocker - Wikipedia

   en.wikipedia.org/wiki/Angiotensin_II_receptor...

   Losartan, the first ARB. Angiotensin II receptor blockers (ARBs), formally angiotensin II receptor type 1 (AT 1) antagonists, [1] also known as angiotensin receptor blockers, [2] [3] angiotensin II receptor antagonists, or AT 1 receptor antagonists, are a group of pharmaceuticals that bind to and inhibit the angiotensin II receptor type 1 (AT 1) and thereby block the arteriolar contraction and ...

5. 2025 NFL mock draft: Expert projections after wild card weekend

   www.aol.com/2025-nfl-mock-draft-expert-142232123...

   Through the wild card round of the playoffs, the top 24 picks in the 2025 NFL draft are locked in.. The Tennessee Titans, Cleveland Browns and New York Giants still hold the top three picks, and ...

6. Putin says Russia is ready to compromise with Trump on ...

   www.aol.com/news/putin-says-russia-getting...

   MOSCOW (Reuters) -Russian President Vladimir Putin said on Thursday that he was ready to compromise over Ukraine in possible talks with U.S. President-elect Donald Trump on ending the war and had ...

7. Beyoncé Makes $2.5 Million Donation to L.A. Fire Relief Funds ...

   www.aol.com/beyonc-makes-2-5-million-111200398.html

   Beyoncé has donated a large sum to support the communities tragically affected by the ongoing wildfires in Los Angeles.. On Sunday, Jan. 12, the singer’s BeyGOOD foundation announced via ...

8. Discovery and development of angiotensin receptor blockers

   en.wikipedia.org/wiki/Discovery_and_development...

   Losartan, valsartan, candesartan, irbesartan, telmisartan and olmesartan all contain a biphenyl-methyl group. Losartan is partly metabolized to its 5- carboxylic acid metabolite EXP 3174, which is a more potent AT 1 receptor antagonist than its parent compound [ 17 ] and has been a model for the continuing development of several other ARBs.

9. Valsartan - Wikipedia

   en.wikipedia.org/wiki/Valsartan

   Valsartan, sold under the brand name Diovan among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. [8] It belongs to a class of medications referred to as angiotensin II receptor blockers (ARBs).