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The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) study stopped its arm of the trial looking at alpha blockers, because doxazosin was less effective than a simple diuretic, and because patients on doxazosin had a 25% higher rate of cardiovascular disease and twice the rate of congestive heart failure as ...
Causes can include: Rheumatic heart disease (a condition that can occur when the bacteria that causes strep throat isn’t treated with antibiotics) Endocarditis (an infection of the inner lining ...
Grade 1 hypertension. The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial, also known as ALLHAT, was a randomized, double-blind, active-controlled study comparing at the same time, four different classes of antihypertensive drugs with the rate of coronary heart disease (CHD) events in ‘high-risk’ people with hypertension. [1]
Biological Toxins such as Diphtheria toxin [19]; Radiation Therapy is known to cause radiation-induced heart disease (RIHD) [20] These agents can lead to varying degrees of cardiotoxicity, and their effects may be dose-dependent and influenced by individual factors such as pre-existing cardiovascular disease and genetic predispositions that can foster greater sensitivity to any cardiac damage.
You wear a seat belt and drive carefully to avoid accidents, you stock up on antioxidant-laden foods to prevent cancer, but you might not realize all the things you should be doing to fight the No ...
AFib, the most common heart rhythm disorder, is linked to a 39% increased risk of cognitive impairment, while coronary heart disease increases the risk of dementia by 27%, with up to 50% of heart ...
Two distinct drug classes in which cardiotoxicity can occur are in anti-cancer and antiarrhythmic drugs. Anti-cancer drug classes that cause cardiotoxicity include anthracyclines, monoclonal antibodies, and antimetabolites. This form generally manifests as a progressive form of heart failure, but can also manifest as an harmful arrhythmia. [2]
Unlike a sudden cardiac event—say, a heart attack—valvular disease develops slowly, over five to 10 years. Many patients don’t experience symptoms until later in the course of disease, if at ...